| Literature DB >> 30443806 |
Jennifer A Pellowski1,2,3, Devon M Price4, Abigail D Harrison5,6, Emily L Tuthill7, Landon Myer8, Don Operario5,6,9, Mark N Lurie6,9,10.
Abstract
A systematic review and meta-analysis was conducted to determine the efficacy of women-focused ART adherence interventions. Included studies (a) reported on a behavioral ART adherence intervention for cis-women living with HIV, (b) measured ART adherence as an outcome, and (c) employed a randomized controlled trial design. Thirteen studies were included in the meta-analysis. Overall, interventions significantly improved ART adherence compared to control conditions (random-effects d = 0.82, 95% CI [0.18, 1.45], p = 0.01), however, this was largely driven by two studies that had effect sizes greater than 3 standard errors above the mean effect size. Key moderators were location, recruitment method, group-based intervention, and alteration of the healthcare system. Innovative behavioral interventions that focus on young women and adolescents, target the critical periods of pregnancy and postpartum and test the integration of multiple levels of intervention to create lasting effects on ART adherence are needed.Entities:
Keywords: ART adherence; Meta-analysis; Randomized controlled trials; Women
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Year: 2019 PMID： 30443806 PMCID： PMC6520201 DOI： 10.1007/s10461-018-2341-9
Source DB: PubMed Journal: AIDS Behav ISSN： 1090-7165