Literature DB >> 2561910

AIDS-associated Kaposi's sarcoma: a molecular model for its pathogenesis.

B Ensoli1, S Z Salahuddin, R C Gallo.   

Abstract

Kaposi's sarcoma is a mesenchymal tumor that is frequently observed in AIDS patients. Although the tumor is clearly associated with HIV-1 infection, little is known about the molecular events underlying its pathogenesis. Here we consider the potential roles of specific cytokines and the virally encoded tat product in inducing the tumor.

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Year:  1989        PMID： 2561910

Source DB:  PubMed          Journal:  Cancer Cells        ISSN： 1042-2196


  7 in total

1.  c-ets1 proto-oncogene is a transcription factor expressed in endothelial cells during tumor vascularization and other forms of angiogenesis in humans.

Authors:  N Wernert; M B Raes; P Lassalle; M P Dehouck; B Gosselin; B Vandenbunder; D Stehelin
Journal:  Am J Pathol       Date:  1992-01       Impact factor: 4.307

Review 2.  Epidemiology and pathogenesis of Kaposi's sarcoma-associated herpesvirus.

Authors:  C Boshoff; R A Weiss
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2001-04-29       Impact factor: 6.237

3.  Oncostatin-M stimulates tyrosine protein phosphorylation in parallel with the activation of p42MAPK/ERK-2 in Kaposi's cells. Evidence that this pathway is important in Kaposi cell growth.

Authors:  M C Amaral; S Miles; G Kumar; A E Nel
Journal:  J Clin Invest       Date:  1993-08       Impact factor: 14.808

4.  Vascular origin of Kaposi's sarcoma. Expression of leukocyte adhesion molecule-1, thrombomodulin, and tissue factor.

Authors:  Y M Zhang; S Bachmann; C Hemmer; J van Lunzen; A von Stemm; P Kern; M Dietrich; R Ziegler; R Waldherr; P P Nawroth
Journal:  Am J Pathol       Date:  1994-01       Impact factor: 4.307

5.  Fibroblast growth factor gene expression in AIDS-Kaposi's sarcoma detected by in situ hybridization.

Authors:  L Xerri; J Hassoun; J Planche; V Guigou; J J Grob; P Parc; D Birnbaum; O deLapeyriere
Journal:  Am J Pathol       Date:  1991-01       Impact factor: 4.307

6.  Kaposi's sarcoma-associated herpesvirus upregulates angiogenin during infection of human dermal microvascular endothelial cells, which induces 45S rRNA synthesis, antiapoptosis, cell proliferation, migration, and angiogenesis.

Authors:  Sathish Sadagopan; Neelam Sharma-Walia; Mohanan Valiya Veettil; Virginie Bottero; Rita Levine; Richard J Vart; Bala Chandran
Journal:  J Virol       Date:  2009-01-21       Impact factor: 5.103

7.  Kaposi's sarcoma-associated herpesvirus induces sustained levels of vascular endothelial growth factors A and C early during in vitro infection of human microvascular dermal endothelial cells: biological implications.

Authors:  Ramu Sivakumar; Neelam Sharma-Walia; Hari Raghu; Mohanan Valiya Veettil; Sathish Sadagopan; Virginie Bottero; Laszlo Varga; Rita Levine; Bala Chandran
Journal:  J Virol       Date:  2007-12-05       Impact factor: 5.103
  7 in total

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