Literature DB >> 25615663

Chemical biology: biosynthetic interceptors.

Niclas Pryk1, Frank Schulz1.   

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Year:  2015        PMID: 25615663     DOI: 10.1038/nchem.2168

Source DB:  PubMed          Journal:  Nat Chem        ISSN: 1755-4330            Impact factor:   24.427


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  11 in total

Review 1.  Merging chemical synthesis and biosynthesis: a new chapter in the total synthesis of natural products and natural product libraries.

Authors:  Andreas Kirschning; Frank Hahn
Journal:  Angew Chem Int Ed Engl       Date:  2012-03-22       Impact factor: 15.336

2.  A method for trapping intermediates of polyketide biosynthesis with a nonhydrolyzable malonyl-coenzyme A analogue.

Authors:  Dieter Spiteller; Claire L Waterman; Jonathan B Spencer
Journal:  Angew Chem Int Ed Engl       Date:  2005-11-04       Impact factor: 15.336

Review 3.  Combinatorial biosynthesis of reduced polyketides.

Authors:  Kira J Weissman; Peter F Leadlay
Journal:  Nat Rev Microbiol       Date:  2005-12       Impact factor: 60.633

4.  Biosynthesis of the antibiotic bacillaene, the product of a giant polyketide synthase complex of the trans-AT family.

Authors:  Jana Moldenhauer; Xiao-Hua Chen; Rainer Borriss; Jörn Piel
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

5.  Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase.

Authors:  Uschi Sundermann; Kenny Bravo-Rodriguez; Stephan Klopries; Susanna Kushnir; Hansel Gomez; Elsa Sanchez-Garcia; Frank Schulz
Journal:  ACS Chem Biol       Date:  2012-11-26       Impact factor: 5.100

6.  Expanding the fluorine chemistry of living systems using engineered polyketide synthase pathways.

Authors:  Mark C Walker; Benjamin W Thuronyi; Louise K Charkoudian; Brian Lowry; Chaitan Khosla; Michelle C Y Chang
Journal:  Science       Date:  2013-09-06       Impact factor: 47.728

7.  In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines.

Authors:  Manuela Tosin; Yuliya Demydchuk; James S Parascandolo; Covadonga Blasco Per; Finian J Leeper; Peter F Leadlay
Journal:  Chem Commun (Camb)       Date:  2011-02-08       Impact factor: 6.222

8.  Insights into lasalocid A ring formation by chemical chain termination in vivo.

Authors:  Manuela Tosin; Luke Smith; Peter F Leadlay
Journal:  Angew Chem Int Ed Engl       Date:  2011-10-24       Impact factor: 15.336

9.  Chemical probes for the functionalization of polyketide intermediates.

Authors:  Elena Riva; Ina Wilkening; Silvia Gazzola; W M Ariel Li; Luke Smith; Peter F Leadlay; Manuela Tosin
Journal:  Angew Chem Int Ed Engl       Date:  2014-09-11       Impact factor: 15.336

Review 10.  Assembly line polyketide synthases: mechanistic insights and unsolved problems.

Authors:  Chaitan Khosla; Daniel Herschlag; David E Cane; Christopher T Walsh
Journal:  Biochemistry       Date:  2014-05-01       Impact factor: 3.162

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