Literature DB >> 25611884

Metal-free, efficient hydrazination of imidazo[1,2-a]pyridine with diethyl azodicarboxylate in neutral media.

Yuanxiang Wang1, Brendan Frett, Nick McConnell, Hong-Yu Li.   

Abstract

The first example of metal-free regioselective hydrazination of imidazo[1,2-a]pyridine with diethyl azodicarboxylate is accomplished. This procedure is chemically appealing due to the high degree of functional group tolerance and efficiency in expanding the molecular diversity.

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Year:  2015        PMID： 25611884      PMCID： PMC4675458          DOI： 10.1039/c4ob02284j

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  48 in total

1.  Behavioural effects of novel benzodiazepine (omega) receptor agonists and partial agonists: increases in punished responding and antagonism of the pentylenetetrazole cue.

Authors:  D.J. Sanger
Journal:  Behav Pharmacol       Date:  1995-03       Impact factor: 2.293

2.  Electrophilic reactivities of azodicarboxylates.

Authors:  Tanja Kanzian; Herbert Mayr
Journal:  Chemistry       Date:  2010-09-10       Impact factor: 5.236

3.  The position of imidazopyridine and metabolic activation are pivotal factors in the antimutagenic activity of novel imidazo[1,2-a]pyridine derivatives.

Authors:  Wael M El-Sayed; Warda A Hussin; Yasair S Al-Faiyz; Mohamed A Ismail
Journal:  Eur J Pharmacol       Date:  2013-06-06       Impact factor: 4.432

4.  Iron-catalyzed oxidative heterocoupling between aliphatic and aromatic organozinc reagents: a novel pathway for functionalized aryl-alkyl cross-coupling reactions.

Authors:  Gérard Cahiez; Laura Foulgoc; Alban Moyeux
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

5.  Novel compounds selectively enhance delta subunit containing GABA A receptors and increase tonic currents in thalamus.

Authors:  K A Wafford; M B van Niel; Q P Ma; E Horridge; M B Herd; D R Peden; D Belelli; J J Lambert
Journal:  Neuropharmacology       Date:  2008-08-13       Impact factor: 5.250

6.  Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines.

Authors:  Mohamed A Ismail; Reem K Arafa; Tanja Wenzler; Reto Brun; Farial A Tanious; W David Wilson; David W Boykin
Journal:  Bioorg Med Chem       Date:  2007-10-18       Impact factor: 3.641

7.  The cellular phenotype of AZ703, a novel selective imidazo[1,2-a]pyridine cyclin-dependent kinase inhibitor.

Authors:  Kate F Byth; Catherine Geh; Cheryl L Forder; Sandra E Oakes; Andrew P Thomas
Journal:  Mol Cancer Ther       Date:  2006-03       Impact factor: 6.261

8.  Hybrid-designed inhibitors of p38 MAP kinase utilizing N-arylpyridazinones.

Authors:  Steven L Colletti; Jessica L Frie; Elizabeth C Dixon; Suresh B Singh; Bernard K Choi; Giovanna Scapin; Catherine E Fitzgerald; Sanjeev Kumar; Elizabeth A Nichols; Stephen J O'Keefe; Edward A O'Neill; Gene Porter; Koppara Samuel; Dennis M Schmatz; Cheryl D Schwartz; Wesley L Shoop; Chris M Thompson; James E Thompson; Ruixiu Wang; Andrea Woods; Dennis M Zaller; James B Doherty
Journal:  J Med Chem       Date:  2003-01-30       Impact factor: 7.446

9.  Iron-catalyzed oxidative cross-coupling of phenols and alkenes.

Authors:  Umesh A Kshirsagar; Clil Regev; Regev Parnes; Doron Pappo
Journal:  Org Lett       Date:  2013-06-11       Impact factor: 6.005

10.  Iron-catalyzed hetero-cross-dehydrogenative coupling reactions of sulfoximines with diarylmethanes: a new route to N-alkylated sulfoximines.

Authors:  Ying Cheng; Wanrong Dong; Long Wang; Kanniyappan Parthasarathy; Carsten Bolm
Journal:  Org Lett       Date:  2014-03-25       Impact factor: 6.005
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  2 in total

1.  Synthesis of Constrained Heterocycles Employing Two Post-Ugi Cyclization Methods for Rapid Library Generation with In Cellulo Activity.

Authors:  Nicholas McConnell; Zhigang Xu; Vishnu Kumarasamy; Daekyu Sun; Brendan Frett; Hong-Yu Li
Journal:  ChemistrySelect       Date:  2017-12-19       Impact factor: 2.109

2.  Selective, C-3 Friedel-Crafts acylation to generate functionally diverse, acetylated Imidazo[1,2-a]pyridine derivatives.

Authors:  Brendan Frett; Nicholas McConnell; Anupreet Kharbanda; Gunaganti Naresh; Benjamin Rounseville; Christina Warner; John Chang; Natalie Debolske; Hong-Yu Li
Journal:  Tetrahedron       Date:  2018-07-17       Impact factor: 2.457
  2 in total

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