| Literature DB >> 12540232 |
Steven L Colletti1, Jessica L Frie, Elizabeth C Dixon, Suresh B Singh, Bernard K Choi, Giovanna Scapin, Catherine E Fitzgerald, Sanjeev Kumar, Elizabeth A Nichols, Stephen J O'Keefe, Edward A O'Neill, Gene Porter, Koppara Samuel, Dennis M Schmatz, Cheryl D Schwartz, Wesley L Shoop, Chris M Thompson, James E Thompson, Ruixiu Wang, Andrea Woods, Dennis M Zaller, James B Doherty.
Abstract
Imidazo[1,2-a]pyridyl N-arylpyridazinones were hybridized from the classic pyridinylimidazoles and the more recent dual hydrogen bond acceptors, resulting in a new structural class of selective p38 MAP kinase inhibitors.Entities:
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Year: 2003 PMID： 12540232 DOI： 10.1021/jm025585h
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446