Literature DB >> 25611503

Dangerous leaks: blood-brain barrier woes in the aging hippocampus.

Costantino Iadecola1.   

Abstract

A leaky blood-brain barrier has long been implicated in cognitive dysfunction in aging and neurodegeneration, but reliable human data were lacking. Here, Montagne et al. (2015) provide the first in vivo evidence of blood-brain barrier disruption in the aging hippocampus and in minimal cognitive impairment.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 25611503      PMCID： PMC4731877          DOI： 10.1016/j.neuron.2014.12.056

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


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