Literature DB >> 2561032

[Molecular mechanism of calcium ion transport in mitochondria. I. Glycoprotein-peptide complex as a component of the electron transport system].

G D Mironova, Zh A Utesheva.   

Abstract

The molecular structure of the mitochondrial glycoprotein capable of forming Ca2+-selective and ruthenium red-sensitive conductance channels when incorporating into a model membrane are studied. The glycoprotein is shown to be a complex consisting of the glycoprotein itself and a low-molecular component which may be attributed to the substance of a peptide nature. A technique is elaborated to divide the complex into constituents. It is found that the channel-forming part of the complex is its peptide component. The glycoprotein component is unable to transport Ca2+ and, probably, fulfills a regulatory function.

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Year:  1989        PMID: 2561032

Source DB:  PubMed          Journal:  Ukr Biokhim Zh (1978)        ISSN: 0201-8470


  4 in total

Review 1.  Pharmacological modulation of mitochondrial calcium homeostasis.

Authors:  Daniela M Arduino; Fabiana Perocchi
Journal:  J Physiol       Date:  2018-02-18       Impact factor: 5.182

2.  Purification of the channel component of the mitochondrial calcium uniporter and its reconstitution into planar lipid bilayers.

Authors:  G D Mironova; M Baumann; O Kolomytkin; Z Krasichkova; A Berdimuratov; T Sirota; I Virtanen; N E Saris
Journal:  J Bioenerg Biomembr       Date:  1994-04       Impact factor: 2.945

Review 3.  The molecular identity of the mitochondrial Ca2+ sequestration system.

Authors:  Anatoly A Starkov
Journal:  FEBS J       Date:  2010-07-26       Impact factor: 5.542

4.  Inhibition of the mitochondrial calcium uniporter by antibodies against a 40-kDa glycoproteinT.

Authors:  N E Saris; T V Sirota; I Virtanen; K Niva; T Penttilä; L P Dolgachova; G D Mironova
Journal:  J Bioenerg Biomembr       Date:  1993-06       Impact factor: 2.945

  4 in total

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