Literature DB >> 25603493

Three New Dimers and Two Monomers of Phenolic Amides from the Fruits of Lycium barbarum and Their Antioxidant Activities.

Kai Gao1, Dongwei Ma2, Yan Cheng3, Xiangrong Tian1, Yunyang Lu1, Xiaoying Du2, Haifeng Tang1,4, Jianzong Chen5.   

Abstract

The aims of this study were to complement the current knowledge on the antioxidative composition of alcohol extracts from the fruits of Lycium barbarum and to evaluate their antioxidant activities. Three new dimers of phenolic amides, named lyciumamides A (3), B (4), and C (5), together with two monomers, N-E-coumaroyl tyramine (1) and N-E-feruloyl tyramine (2), were isolated from the fruits for the first time with the help of activity-guided chromatography. Compounds 1-5 were evaluated for their antioxidant activities in scavenging 2,2-diphenyl-1-picrylhydrazyl free radical and inhibiting lipid peroxidation in rat liver microsomes induced by ascorbate/Fe2+, cumine hydroperoxide, or CCl4/reduced form of nicotinamide-adenine dinucleotide phosphate, and the results showed that all of them exhibited strong activities, whereas compounds 1 and 2 were more potent than the reference tert-butyl-4-hydroxyanisole.

Entities:  

Keywords:  Lycium barbarum; N-E-coumaroyl tyramine; N-E-feruloyl tyramine; antioxidant activities; lyciumamide; phenolic amides

Year:  2015        PMID： 25603493     DOI： 10.1021/jf5049222

Source DB:  PubMed          Journal:  J Agric Food Chem        ISSN： 0021-8561            Impact factor:   5.279


  12 in total

1.  Lyciumamide A, a dimer of phenolic amide, protects against NMDA-induced neurotoxicity and potential mechanisms in vitro.

Authors:  Kai Gao; Meiyou Liu; Yuan Li; Lei Wang; Chao Zhao; Xian Zhao; Jinyi Zhao; Yi Ding; Haifeng Tang; Yanyan Jia; Jingwen Wang; Aidong Wen
Journal:  J Mol Histol       Date:  2021-03-23       Impact factor: 2.611

2.  Determination of Biogenic Amines in Different Parts of Lycium barbarum L. by HPLC with Precolumn Dansylation.

Authors:  Yun Ai; Yan Ni Sun; Li Liu; Fang Yuan Yao; Yan Zhang; Feng Yi Guo; Wen Jie Zhao; Jian Li Liu; Ning Zhang
Journal:  Molecules       Date:  2021-02-17       Impact factor: 4.411

3.  The Anticancer Activities Phenolic Amides from the Stem of Lycium barbarum.

Authors:  Pei-Feng Zhu; Zhi Dai; Bei Wang; Xin Wei; Hao-Fei Yu; Zi-Ru Yan; Xu-Dong Zhao; Ya-Ping Liu; Xiao-Dong Luo
Journal:  Nat Prod Bioprospect       Date:  2017-06-06

Review 4.  Systematic Review of Chemical Constituents in the Genus Lycium (Solanaceae).

Authors:  Dan Qian; Yaxing Zhao; Guang Yang; Luqi Huang
Journal:  Molecules       Date:  2017-06-08       Impact factor: 4.411

5.  Analysis of Phenolic Compounds in Commercial Cannabis sativa L. Inflorescences Using UHPLC-Q-Orbitrap HRMS.

Authors:  Luana Izzo; Luigi Castaldo; Alfonso Narváez; Giulia Graziani; Anna Gaspari; Yelko Rodríguez-Carrasco; Alberto Ritieni
Journal:  Molecules       Date:  2020-01-31       Impact factor: 4.411

6.  Bioactive Diarylheptanoids from Alpinia coriandriodora.

Authors:  Xiao-Li Cheng; Han-Xiang Li; Juan Chen; Ping Wu; Jing-Hua Xue; Zhong-Yu Zhou; Nia-He Xia; Xiao-Yi Wei
Journal:  Nat Prod Bioprospect       Date:  2020-09-09

7.  Diversity and spatiotemporal dynamics of fungal communities in the rhizosphere soil of Lycium barbarum L.: a new insight into the mechanism of geoherb formation.

Authors:  Yuekun Li; Kaili Chen; Siyang Liu; Xiaojie Liang; Yajun Wang; Xuan Zhou; Yue Yin; Youlong Cao; Wei An; Ken Qin; Yanfei Sun
Journal:  Arch Microbiol       Date:  2022-02-26       Impact factor: 2.552

8.  Two novel oxetane containing lignans and a new megastigmane from Paronychia arabica and in silico analysis of them as prospective SARS-CoV-2 inhibitors.

Authors:  Abdelsamed I Elshamy; Tarik A Mohamed; Mahmoud A A Ibrahim; Mohamed A M Atia; Tatsuro Yoneyama; Akemi Umeyama; Mohamed-Elamir F Hegazy
Journal:  RSC Adv       Date:  2021-06-04       Impact factor: 4.036

9.  A phenolic amide (LyA) isolated from the fruits of Lycium barbarum protects against cerebral ischemia-reperfusion injury via PKCε/Nrf2/HO-1 pathway.

Authors:  Kai Gao; Meiyou Liu; Yi Ding; Minna Yao; Yanrong Zhu; Jinyi Zhao; Lianghua Cheng; Juan Bai; Fan Wang; Jinyi Cao; Jiankang Li; Haifeng Tang; Yanyan Jia; Aidong Wen
Journal:  Aging (Albany NY)       Date:  2019-12-26       Impact factor: 5.682

10.  Preparative Separation of Flavonoids from Goji Berries by Mixed-Mode Macroporous Adsorption Resins and Effect on Aβ-Expressing and Anti-Aging Genes.

Authors:  Jianfei Liu; Jiao Meng; Jinhao Du; Xiaofeng Liu; Qiaosheng Pu; Duolong Di; Chang Chen
Journal:  Molecules       Date:  2020-07-31       Impact factor: 4.411
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