Literature DB >> 25601704

Improved ion optics for introduction of ions into a 9.4-T Fourier transform ion cyclotron resonance mass spectrometer.

Yu Chen1, Franklin E Leach, Nathan K Kaiser, Xibei Dang, Yehia M Ibrahim, Randolph V Norheim, Gordon A Anderson, Richard D Smith, Alan G Marshall.   

Abstract

Enhancements to the ion source and transfer optics of our 9.4 T Fourier transform ion cyclotron resonance (ICR) mass spectrometer have resulted in improved ion transmission efficiency for more sensitive mass measurement of complex mixtures at the MS and MS/MS levels. The tube lens/skimmer has been replaced by a dual ion funnel and the following octopole by a quadrupole for reduced ion cloud radial expansion before transmission into a mass-selective quadrupole. The number of ions that reach the ICR cell is increased by an order of magnitude for the funnel/quadrupole relative to the tube lens/skimmer/octopole.
Copyright © 2015 John Wiley & Sons, Ltd.

Entities:  

Keywords:  FT MS; ICR; ion funnel; mass selection; quadrupole ion guide

Mesh：

Substances：

Year:  2015        PMID： 25601704      PMCID： PMC4300554          DOI： 10.1002/jms.3523

Source DB:  PubMed          Journal:  J Mass Spectrom        ISSN： 1076-5174            Impact factor:   1.982


  19 in total

1.  Charge capacity limitations of radio frequency ion guides in their use for improved ion accumulation and trapping in mass spectrometry.

Authors:  A V Tolmachev; H R Udseth; R D Smith
Journal:  Anal Chem       Date:  2000-03-01       Impact factor: 6.986

2.  Initial implementation of an electrodynamic ion funnel with Fourier transform ion cyclotron resonance mass spectrometry.

Authors:  M E Belov; M V Gorshkov; H R Udseth; G A Anderson; A V Tolmachev; D C Prior; R Harkewicz; R D Smith
Journal:  J Am Soc Mass Spectrom       Date:  2000-01       Impact factor: 3.109

3.  Baseline mass resolution of peptide isobars: a record for molecular mass resolution.

Authors:  F He; C L Hendrickson; A G Marshall
Journal:  Anal Chem       Date:  2001-02-01       Impact factor: 6.986

4.  Extraction, purification and analysis of histones.

Authors:  David Shechter; Holger L Dormann; C David Allis; Sandra B Hake
Journal:  Nat Protoc       Date:  2007       Impact factor: 13.491

5.  Electron capture dissociation implementation progress in Fourier transform ion cyclotron resonance mass spectrometry.

Authors:  Yury O Tsybin; John P Quinn; Oleg Yu Tsybin; Christopher L Hendrickson; Alan G Marshall
Journal:  J Am Soc Mass Spectrom       Date:  2008-03-04       Impact factor: 3.109

Review 6.  Fourier transform ion cyclotron resonance mass spectrometry: a primer.

Authors:  A G Marshall; C L Hendrickson; G S Jackson
Journal:  Mass Spectrom Rev       Date:  1998 Jan-Feb       Impact factor: 10.946

7.  Electrically compensated Fourier transform ion cyclotron resonance cell for complex mixture mass analysis.

Authors:  Nathan K Kaiser; Joshua J Savory; Amy M McKenna; John P Quinn; Christopher L Hendrickson; Alan G Marshall
Journal:  Anal Chem       Date:  2011-08-12       Impact factor: 6.986

8.  Space charge effects in Fourier transform mass spectrometry. Mass calibration.

Authors:  E B Ledford; D L Rempel; M L Gross
Journal:  Anal Chem       Date:  1984-12       Impact factor: 6.986

9.  A novel Fourier transform ion cyclotron resonance mass spectrometer with improved ion trapping and detection capabilities.

Authors:  Nathan K Kaiser; Gunnar E Skulason; Chad R Weisbrod; James E Bruce
Journal:  J Am Soc Mass Spectrom       Date:  2009-01-07       Impact factor: 3.109

10.  Counting individual sulfur atoms in a protein by ultrahigh-resolution Fourier transform ion cyclotron resonance mass spectrometry: experimental resolution of isotopic fine structure in proteins.

Authors:  S D Shi; C L Hendrickson; A G Marshall
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-29       Impact factor: 11.205
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  2 in total

Review 1.  Towards Higher Sensitivity of Mass Spectrometry: A Perspective From the Mass Analyzers.

Authors:  Chang Li; Shiying Chu; Siyuan Tan; Xinchi Yin; You Jiang; Xinhua Dai; Xiaoyun Gong; Xiang Fang; Di Tian
Journal:  Front Chem       Date:  2021-12-21       Impact factor: 5.221

Review 2.  Applications of MALDI-MS/MS-Based Proteomics in Biomedical Research.

Authors:  Laura Darie-Ion; Danielle Whitham; Madhuri Jayathirtha; Yashveen Rai; Anca-Narcisa Neagu; Costel C Darie; Brînduşa Alina Petre
Journal:  Molecules       Date:  2022-09-21       Impact factor: 4.927
  2 in total

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