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24 in total

Review 1. Structure-activity relationships of the fluoroquinolones.

Authors: D T Chu; P B Fernandes
Journal: Antimicrob Agents Chemother Date: 1989-02 Impact factor: 5.191

2. Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes.

Authors: L L Shen; W E Kohlbrenner; D Weigl; J Baranowski
Journal: J Biol Chem Date: 1989-02-15 Impact factor: 5.157

3. Clinical use of the quinolones.

Authors: H C Neu
Journal: Lancet Date: 1987-12-05 Impact factor: 79.321

4. A-61827 (A-60969), a new fluoronaphthyridine with activity against both aerobic and anaerobic bacteria.

Authors: P B Fernandes; D T Chu; R N Swanson; N R Ramer; C W Hanson; R R Bower; J M Stamm; D J Hardy
Journal: Antimicrob Agents Chemother Date: 1988-01 Impact factor: 5.191

5. Chiral DNA gyrase inhibitors. 1. Synthesis and antimicrobial activity of the enantiomers of 6-fluoro-7-(1-piperazinyl)-1-(2'-trans-phenyl-1'-cyclopropyl)-1, 4-dihydro-4-oxoquinoline-3-carboxylic acid.

Authors: L A Mitscher; P N Sharma; D T Chu; L L Shen; A G Pernet
Journal: J Med Chem Date: 1986-10 Impact factor: 7.446

6. New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay.

Authors: J M Domagala; L D Hanna; C L Heifetz; M P Hutt; T F Mich; J P Sanchez; M Solomon
Journal: J Med Chem Date: 1986-03 Impact factor: 7.446

Review 3. Use of quinolones in pediatrics.

Authors: U B Schaad
Journal: Eur J Clin Microbiol Infect Dis Date: 1991-04 Impact factor: 3.267

3 in total

Value of new quinolones in the treatment and prophylaxis of infectious diseases: introductory remarks.

Review 1. Structure-activity relationships of the fluoroquinolones.

2. Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes.

3. Clinical use of the quinolones.

4. A-61827 (A-60969), a new fluoronaphthyridine with activity against both aerobic and anaerobic bacteria.

5. Chiral DNA gyrase inhibitors. 1. Synthesis and antimicrobial activity of the enantiomers of 6-fluoro-7-(1-piperazinyl)-1-(2'-trans-phenyl-1'-cyclopropyl)-1, 4-dihydro-4-oxoquinoline-3-carboxylic acid.

6. New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay.

Review 7. Fluoroquinolone antibiotics. Microbiology, pharmacokinetics and clinical use.

Review 8. Aspects of chemistry in the development of the 4-quinolone antibacterial agents.

9. Nalidixic acid resistance: a second genetic character involved in DNA gyrase activity.

10. Comparative in vitro activity of PD 127,391, a new fluorinated 4-quinolone derivative.

1. Clinical role of the quinolones today and in the future.

2. Treating acute urinary tract infections. An RCT of 3-day versus 7-day norfloxacin.

Review 3. Use of quinolones in pediatrics.