Literature DB >> 2558856

The human mineralocorticoid receptor gene (MLR) is located on chromosome 4 at q31.2.

Y S Fan1, R L Eddy, M G Byers, L L Haley, W M Henry, N J Nowak, T B Shows.   

Abstract

The gene for the human mineralocorticoid receptor (MLR) was previously localized to chromosome 4. Here, we have localized this gene to 4q31.2 by in situ hybridization. This precise mapping of MLR will assist in the linkage analysis and genetic characterization of pseudohypoaldosteronism, an autosomal recessive disorder which likely results from a defect in the MLR gene.

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Year:  1989        PMID: 2558856     DOI: 10.1159/000132846

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  6 in total

1.  Mapping small DNA sequences by fluorescence in situ hybridization directly on banded metaphase chromosomes.

Authors:  Y S Fan; L M Davis; T B Shows
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205

2.  Colocalization of the genes coding for the alpha 3 and beta 3 subunits of soluble guanylyl cyclase to human chromosome 4 at q31.3-q33.

Authors:  G Giuili; N Roechel; U Scholl; M G Mattei; G Guellaen
Journal:  Hum Genet       Date:  1993-04       Impact factor: 4.132

3.  Regional chromosomal assignment of the human mineralocorticoid receptor gene to 4q31.1.

Authors:  N Morrison; S B Harrap; J L Arriza; E Boyd; J M Connor
Journal:  Hum Genet       Date:  1990-06       Impact factor: 4.132

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  6 in total

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