Literature DB >> 25588099

Functional chromatographic technique for natural product isolation.

Eric C Lau1, Damian J Mason, Nicole Eichhorst, Pearce Engelder, Celestina Mesa, E M Kithsiri Wijeratne, G M Kamal B Gunaherath, A A Leslie Gunatilaka, James J La Clair, Eli Chapman.   

Abstract

Natural product discovery arises through a unique interplay between chromatographic purification and biological assays. Currently, most techniques used for natural product purification deliver leads without a defined biological action. We now describe a technique, referred to herein as functional chromatography, that deploys biological affinity as the matrix for compound isolation.

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Year:  2015        PMID： 25588099      PMCID： PMC4576851          DOI： 10.1039/c4ob02292k

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  52 in total

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  6 in total

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