| Literature DB >> 25584794 |
Didier Y R Stainier1, Zacharias Kontarakis2, Andrea Rossi2.
Abstract
The morpholino anti-sense technology has been used extensively to test gene function. The zebrafish model allows a detailed comparison of knockdown (anti-sense) and knockout (mutation) effects. Recent studies reveal that these two approaches can often lead to surprisingly different phenotypes, thus raising a number of important questions.Entities:
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Year: 2015 PMID: 25584794 DOI: 10.1016/j.devcel.2014.12.012
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270