Kopal Sharma1, Amit Sharma2, Ml Aseri3, Angelika Batta4, Vikas Singh2, Dinesh Pilania5, Yogesh Kumar Sharma5. 1. Senior Demonstrator, Department of Pharmacology, Mahatma Gandhi Medical College & Hospital , Jaipur, India . 2. Reader, Department of Oral & Maxillofacial Surgery, Rajasthan Dental College , Jaipur, India . 3. Ex. Professor & Head, Department of Pharmacology, JLN Medical College , Ajmer, India . 4. PG Student, Department of Pharmacology, Mahatma Gandhi Medical College & Hospital , Jaipur, India . 5. Senior Lecturer, Department of Oral & Maxillofacial Surgery, Rajasthan Dental College , Jaipur, India .
Abstract
BACKGROUND: Pain control is one of the most important factors for successful treatment. Each new measure to control pain has been looked as miraculous act at the initial stages. The improvements in agents and techniques for local anaesthesia are probably the most important advances in dental science to have occurred in the past years. AIM: To evaluate 4% articaine hydrochloride against 2% lignocaine hydrochloride anaesthesia in providing adequate palatal anaesthesia in maxillary posterior regions, without the need for a palatal block. SETTINGS AND DESIGN: Healthy patients above 15 y of age and requiring bilateral extraction of their maxillary posterior teeth were included in this crossover study. The exclusion criteria included medical history of cardiovascular and kidney diseases, gastrointestinal bleeding or ulceration, allergic reactions to local anaesthetic, pregnancy or current lactation. MATERIALS AND METHODS: Eighty patients, requiring bilateral extraction of their teeth due to various reasons were enrolled for this study. Each patient received both lignocaine and articaine anaesthetic in equivalent dose at two different appointments. Maxillary infiltration technique was used for extraction of maxillary posterior teeth at both the appointments. A 170-mm Heft Parker visual analogue scale was used to assess the pain on the palatal mucosa after buccal infiltration of either anaesthetic agent. Blood pressure, Pulse rate and electrocardiographic monitoring were done during the procedure. Adverse effects during the study period were also monitored. STATISTICAL ANALYSIS: Data was analysed by Z-test and student's t-test. RESULTS: Pain scores on probing palatal mucosa after buccal infiltration of the anaesthetic were more for lignocaine as compare to articaine and it was statistically significant (p <.001). However, for hemodynamic parameters and electrocardiographic monitoring, there was no statistically significant difference in blood pressure, pulse rate and electrocardiograph before and after the completion of extraction (p > 0.05). CONCLUSION: Four percent articaine offers better clinical performance than 2% Lignocaine, particularly in terms of providing adequate palatal anaesthesia with only buccal infiltration.
BACKGROUND:Pain control is one of the most important factors for successful treatment. Each new measure to control pain has been looked as miraculous act at the initial stages. The improvements in agents and techniques for local anaesthesia are probably the most important advances in dental science to have occurred in the past years. AIM: To evaluate 4% articaine hydrochloride against 2% lignocaine hydrochloride anaesthesia in providing adequate palatal anaesthesia in maxillary posterior regions, without the need for a palatal block. SETTINGS AND DESIGN: Healthy patients above 15 y of age and requiring bilateral extraction of their maxillary posterior teeth were included in this crossover study. The exclusion criteria included medical history of cardiovascular and kidney diseases, gastrointestinal bleeding or ulceration, allergic reactions to local anaesthetic, pregnancy or current lactation. MATERIALS AND METHODS: Eighty patients, requiring bilateral extraction of their teeth due to various reasons were enrolled for this study. Each patient received both lignocaine and articaine anaesthetic in equivalent dose at two different appointments. Maxillary infiltration technique was used for extraction of maxillary posterior teeth at both the appointments. A 170-mm Heft Parker visual analogue scale was used to assess the pain on the palatal mucosa after buccal infiltration of either anaesthetic agent. Blood pressure, Pulse rate and electrocardiographic monitoring were done during the procedure. Adverse effects during the study period were also monitored. STATISTICAL ANALYSIS: Data was analysed by Z-test and student's t-test. RESULTS:Pain scores on probing palatal mucosa after buccal infiltration of the anaesthetic were more for lignocaine as compare to articaine and it was statistically significant (p <.001). However, for hemodynamic parameters and electrocardiographic monitoring, there was no statistically significant difference in blood pressure, pulse rate and electrocardiograph before and after the completion of extraction (p > 0.05). CONCLUSION: Four percent articaine offers better clinical performance than 2% Lignocaine, particularly in terms of providing adequate palatal anaesthesia with only buccal infiltration.
Authors: Bella L Colombini; Karin C S Modena; Adriana M Calvo; Vivien T Sakai; Fernando P M Giglio; Thiago J Dionísio; Alceu S Trindade; José R P Lauris; Carlos F Santos Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Date: 2006-03-24
Authors: Paul A Moore; Sean G Boynes; Elliot V Hersh; Scott S DeRossi; Thomas P Sollecito; J Max Goodson; Juliana S Leonel; Constantinos Floros; Carrie Peterson; Matthew Hutcheson Journal: J Am Dent Assoc Date: 2006-11 Impact factor: 3.634