| Literature DB >> 25583206 |
Yasunori Akutsu1, Hisahiro Matsubara2.
Abstract
Esophageal cancer is thought to be the most malignant neoplasm due to its biological aggressiveness. The most effective treatment modality for esophageal cancer, particularly T4 esophageal cancer, is chemoradiotherapy (CRT). Some T4 patients show long-term survival after receiving CRT, suggesting that even T4 esophageal cancer can be cured with this modality. Although surgery is performed after CRT in some T4 cases, its prognostic benefit is controversial. In this paper, we review the status of CRT and conversion surgery as well as the development of new regimens and discuss the future prospects of CRT in the treatment of T4 esophageal cancer in Japan.Entities:
Keywords: Chemoradiotherapy; Esophageal cancer; Japan; Surgery; T4
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Year: 2015 PMID: 25583206 DOI: 10.1007/s00595-015-1116-4
Source DB: PubMed Journal: Surg Today ISSN: 0941-1291 Impact factor: 2.549