Literature DB >> 2557618

Identification of cell surface receptors for the 86-kilodalton glycoprotein of human cytomegalovirus.

S Keay1, T C Merigan, L Rasmussen.   

Abstract

Cell surface receptors for the 86-kDa glycoprotein (gp86) of human cytomegalovirus (HCMV) were identified by using two monoclonal anti-idiotype antibodies that bear the internal image of gp86. These antibodies bound to cells permissive for HCMV infection by both ELISA and immunofluorescence assay and inhibited HCMV plaque formation in human embryonic lung (HEL) cells. Immunoblot analysis showed specific binding of both internal image anti-idiotype antibodies as well as gp86 to an HEL cell membrane protein with an approximate molecular mass of 92.5 kDa. In addition, immunoprecipitation of radiolabeled membrane and cell surface proteins from human foreskin tissue, human foreskin fibroblasts, or HEL cells showed specific binding of anti-idiotype antibody predominantly to the 92.5-kDa protein.

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Year:  1989        PMID： 2557618      PMCID： PMC298652          DOI： 10.1073/pnas.86.24.10100

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  25 in total

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Review 2.  Idiotypic mimicry of biological receptors.

Authors:  G N Gaulton; M I Greene
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4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

5.  Cytomegalovirus strain AD169 binds beta 2 microglobulin in vitro after release from cells.

Authors:  J E Grundy; J A McKeating; P D Griffiths
Journal:  J Gen Virol       Date:  1987-03       Impact factor: 3.891

6.  The properties and sequence of glycoprotein H of herpes simplex virus type 1.

Authors:  U Gompels; A Minson
Journal:  Virology       Date:  1986-09       Impact factor: 3.616

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Authors:  L Rasmussen; J Mullenax; R Nelson; T C Merigan
Journal:  J Virol       Date:  1985-08       Impact factor: 5.103

8.  Murine monoclonal antibody to a single protein neutralizes the infectivity of human cytomegalovirus.

Authors:  L E Rasmussen; R M Nelson; D C Kelsall; T C Merigan
Journal:  Proc Natl Acad Sci U S A       Date:  1984-02       Impact factor: 11.205

9.  Isolation and biochemical characterization of the mammalian reovirus type 3 cell-surface receptor.

Authors:  M S Co; G N Gaulton; B N Fields; M I Greene
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205

10.  Virus-specific IgG and IgM antibodies in normal and immunocompromised subjects infected with cytomegalovirus.

Authors:  L Rasmussen; D Kelsall; R Nelson; W Carney; M Hirsch; D Winston; J Preiksaitis; T C Merigan
Journal:  J Infect Dis       Date:  1982-02       Impact factor: 5.226
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  31 in total

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2.  The human fibroblast receptor for gp86 of human cytomegalovirus is a phosphorylated glycoprotein.

Authors:  S Keay; B Baldwin
Journal:  J Virol       Date:  1992-08       Impact factor: 5.103

3.  Characterization of human cytomegalovirus glycoprotein-induced cell-cell fusion.

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Review 4.  Epstein-Barr virus tissue tropism: a major determinant of immunopathogenesis.

Authors:  L Hutt-Fletcher
Journal:  Springer Semin Immunopathol       Date:  1991

Review 5.  Heterogeneous pathways of maternal-fetal transmission of human viruses (review).

Authors:  A Saleh Younes; Márta Csire; Beatrix Kapusinszky; Katalin Szomor; Mária Takács; György Berencsi
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6.  Anti-idiotypic mimicry of a neutralizing epitope on the glycoprotein B complex of human cytomegalovirus.

Authors:  E S Tackaberry; J Hamel; Y Larose; B R Brodeur
Journal:  J Virol       Date:  1993-11       Impact factor: 5.103

7.  Definition of a subset of human peripheral blood mononuclear cells that are permissive to human cytomegalovirus infection.

Authors:  C Söderberg; S Larsson; S Bergstedt-Lindqvist; E Möller
Journal:  J Virol       Date:  1993-06       Impact factor: 5.103

8.  Transcriptional activation of cellular oncogenes fos, jun, and myc by human cytomegalovirus.

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Journal:  J Virol       Date:  1991-03       Impact factor: 5.103

9.  Coiled-coil domains in glycoproteins B and H are involved in human cytomegalovirus membrane fusion.

Authors:  Matthew Lopper; Teresa Compton
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10.  CD13 (human aminopeptidase N) mediates human cytomegalovirus infection.

Authors:  C Söderberg; T D Giugni; J A Zaia; S Larsson; J M Wahlberg; E Möller
Journal:  J Virol       Date:  1993-11       Impact factor: 5.103
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