Literature DB >> 2557003

Evidence for tight metabolic control of the receptor-activated polyphosphoinositide cycle in human platelets.

V M Steen1, O B Tysnes, H Holmsen.   

Abstract

The [32P]PIP2/[32P]PA and the [32P]PIP/[32P]PA relationships were demonstrated to be remarkably similar after stimulation of [32P]Pi-prelabelled platelets for 90 s with various combinations and concentrations of agonists and inhibitors. Thus the activity of the PI and PIP kinases with the corresponding phosphomonoesterases may be tightly controlled during receptor-mediated platelet stimulation involving phospholipase C activation.

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Year:  1989        PMID： 2557003      PMCID： PMC1133474          DOI： 10.1042/bj2630621

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  21 in total

Review 1.  Inositol phosphates: proliferation, metabolism and function.

Authors:  R F Irvine; R M Moor; W K Pollock; P M Smith; K A Wreggett
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1988-07-26       Impact factor: 6.237

Review 2.  Regulation of platelet phospholipase C.

Authors:  S E Rittenhouse; H S Banga; J P Sasson; W G King; A P Tarver
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1988-07-26       Impact factor: 6.237

3.  The synergistic effect of serotonin and epinephrine on the human platelet at the level of signal transduction.

Authors:  D de Chaffoy de Courcelles; P Roevens; H Van Belle; F De Clerck
Journal:  FEBS Lett       Date:  1987-07-27       Impact factor: 4.124

4.  Kinetics of the thrombin-induced release of calcium (II) by platelets.

Authors:  T C Detwiler; R D Feinman
Journal:  Biochemistry       Date:  1973-01-16       Impact factor: 3.162

Review 5.  Na+/H+ exchange as a modulator of platelet activation.

Authors:  W Siffert; J W Akkerman
Journal:  Trends Biochem Sci       Date:  1988-04       Impact factor: 13.807

6.  Dissociation of thrombin from platelets by hirudin. Evidence for receptor processing.

Authors:  S W Tam; J W Fenton; T C Detwiler
Journal:  J Biol Chem       Date:  1979-09-25       Impact factor: 5.157

7.  Neomycin inhibits platelet functions and inositol phospholipid metabolism upon stimulation with thrombin, but not with ionomycin or 12-O-tetradecanoyl-phorbol 13-acetate.

Authors:  O B Tysnes; V M Steen; H Holmsen
Journal:  Eur J Biochem       Date:  1988-10-15

8.  Synergism between thrombin and adrenaline (epinephrine) in human platelets. Marked potentiation of inositol phospholipid metabolism.

Authors:  V M Steen; O B Tysnes; H Holmsen
Journal:  Biochem J       Date:  1988-07-15       Impact factor: 3.857

9.  Activation of human platelet phospholipase C by ionophore A23187 is totally dependent upon cyclo-oxygenase products and ADP.

Authors:  S E Rittenhouse
Journal:  Biochem J       Date:  1984-08-15       Impact factor: 3.857

10.  A role for Gi in control of thrombin receptor-phospholipase C coupling in human platelets.

Authors:  M F Crouch; E G Lapetina
Journal:  J Biol Chem       Date:  1988-03-05       Impact factor: 5.157
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  2 in total

1.  Neomycin does not interfere with the inositol phospholipid metabolism, but blocks binding of alpha-thrombin to intact human platelets.

Authors:  O B Tysnes; E Johanessen; V M Steen
Journal:  Biochem J       Date:  1991-01-01       Impact factor: 3.857

2.  Protein kinase C promotes restoration of calcium homeostasis to platelet activating factor-stimulated human neutrophils by inhibition of phospholipase C.

Authors:  Gregory R Tintinger; Annette J Theron; Helen C Steel; Riana Cockeran; Lynette Pretorius; Ronald Anderson
Journal:  J Inflamm (Lond)       Date:  2009-10-30       Impact factor: 4.981
  2 in total

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