Literature DB >> 25569801

Rapid ultrasonic isothermal amplification of DNA with multiplexed melting analysis – applications in the clinical diagnosis of sexually transmitted diseases.

Gaolian Xu1, Rory N Gunson, Jonathan M Cooper, Julien Reboud.   

Abstract

We describe a nucleic acid testing (NAT) platform for infectious disease diagnostics at the point-of-care, using surface acoustic waves (SAW) to perform a multiplexed loop-mediated isothermal amplification (LAMP) test for sexually transmitted diseases. The ultrasonic actuation not only enables faster NAT reactions but also provides a route towards integrating low-cost, low-power molecular diagnostics into disposable sensors.

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Year:  2015        PMID: 25569801     DOI: 10.1039/c4cc08389j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  10 in total

1.  Loop-Mediated Isothermal Amplification (LAMP) for Rapid Detection and Quantification of Dehalococcoides Biomarker Genes in Commercial Reductive Dechlorinating Cultures KB-1 and SDC-9.

Authors:  Yogendra H Kanitkar; Robert D Stedtfeld; Robert J Steffan; Syed A Hashsham; Alison M Cupples
Journal:  Appl Environ Microbiol       Date:  2016-01-08       Impact factor: 4.792

2.  A point of care platform based on microfluidic chip for nucleic acid extraction in less than 1 minute.

Authors:  Jianzhong Zhang; Xiaosong Su; Jiasu Xu; Jin Wang; Juntian Zeng; Caiyu Li; Wendi Chen; Tingdong Li; Xiaoping Min; Dongxu Zhang; Shiyin Zhang; Shengxiang Ge; Jun Zhang; Ningshao Xia
Journal:  Biomicrofluidics       Date:  2019-05-08       Impact factor: 2.800

3.  Diagnosis of Neisseria Gonorrhoeae by Loop-Mediated Isothermal Amplification: Systematic Review and Meta-Analysis.

Authors:  Qian Zhou; Ruixing Yu; Deju Xia; Jingwei Liu; Wenqi Xu; Yueping Yin
Journal:  Indian J Microbiol       Date:  2022-04-21

4.  A Cell-Phone-Based Acoustofluidic Platform for Quantitative Point-of-Care Testing.

Authors:  Liying Zhang; Zhenhua Tian; Hunter Bachman; Peiran Zhang; Tony Jun Huang
Journal:  ACS Nano       Date:  2020-03-02       Impact factor: 15.881

Review 5.  Bridging the gap between development of point-of-care nucleic acid testing and patient care for sexually transmitted infections.

Authors:  Kuangwen Hsieh; Johan H Melendez; Charlotte A Gaydos; Tza-Huei Wang
Journal:  Lab Chip       Date:  2022-02-01       Impact factor: 7.517

6.  Bacteria Murmur: Application of an Acoustic Biosensor for Plant Pathogen Detection.

Authors:  George Papadakis; Nicholas Skandalis; Anastasia Dimopoulou; Paraskevas Glynos; Electra Gizeli
Journal:  PLoS One       Date:  2015-07-15       Impact factor: 3.240

7.  A capillary-based multiplexed isothermal nucleic acid-based test for sexually transmitted diseases in patients.

Authors:  Gaolian Xu; Hang Zhao; Jonathan M Cooper; Julien Reboud
Journal:  Chem Commun (Camb)       Date:  2016-10-06       Impact factor: 6.222

8.  Programmable design of isothermal nucleic acid diagnostic assays through abstraction-based models.

Authors:  Gaolian Xu; Julien Reboud; Yunfei Guo; Hao Yang; Hongchen Gu; Chunhai Fan; Xiaohua Qian; Jonathan M Cooper
Journal:  Nat Commun       Date:  2022-03-28       Impact factor: 14.919

9.  Facile construction of a highly sensitive DNA biosensor by in-situ assembly of electro-active tags on hairpin-structured probe fragment.

Authors:  Qingxiang Wang; Feng Gao; Jiancong Ni; Xiaolei Liao; Xuan Zhang; Zhenyu Lin
Journal:  Sci Rep       Date:  2016-03-02       Impact factor: 4.379

10.  Paper-Origami-Based Multiplexed Malaria Diagnostics from Whole Blood.

Authors:  Gaolian Xu; Debbie Nolder; Julien Reboud; Mary C Oguike; Donelly A van Schalkwyk; Colin J Sutherland; Jonathan M Cooper
Journal:  Angew Chem Int Ed Engl       Date:  2016-08-24       Impact factor: 15.336

  10 in total

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