M G McCormack1, A J Smith2, A N Akram3, M Jackson1, D Robertson1, G Edwards4. 1. College of Medical, Veterinary & Life Sciences, Glasgow Dental Hospital & School, University of Glasgow, Glasgow, Scotland, UK. 2. College of Medical, Veterinary & Life Sciences, Glasgow Dental Hospital & School, University of Glasgow, Glasgow, Scotland, UK. Electronic address: Andrew.smith@glasgow.ac.uk. 3. Govan Dental Care, Glasgow, Scotland, UK. 4. Scottish MRSA Reference Laboratory, Glasgow Royal Infirmary, Glasgow, Scotland, UK.
Abstract
BACKGROUND: The role of intraoral Staphylococcus aureus in disease and cross-infection sources is controversial. We present a 10-year retrospective analysis of laboratory data reporting isolation of S aureus from oral and perioral clinical specimens. METHODS: A review of laboratory records for specimens where S aureus was isolated were collated and analyzed from January 1998-December 2007 at the Oral Microbiology Laboratory, Glasgow Dental Hospital. RESULTS: There were 11,312 specimens submitted to the laboratory over the study time period. S aureus was isolated from 1,986 specimens (18%). Of these, 1,782 (90%) were methicillin-sensitive S aureus (MSSA), and 204 (10%) were methicillin-resistant S aureus (MRSA). The most common specimen type from which MSSA was isolated was an oral rinse, whereas for MRSA this was a tongue swab. Most of the MRSA isolates were EMRSA-15 or EMRSA-16 lineage. CONCLUSION: These findings suggest that S aureus continues to be a frequent isolate in the oral cavity and perioral region. The oral cavity should be considered a source of S aureus in terms of cross-infection and dissemination to other body sites. The role of S aureus in the pathogenesis of certain oral diseases should also be considered as part of a differential diagnosis.
BACKGROUND: The role of intraoral Staphylococcus aureus in disease and cross-infection sources is controversial. We present a 10-year retrospective analysis of laboratory data reporting isolation of S aureus from oral and perioral clinical specimens. METHODS: A review of laboratory records for specimens where S aureus was isolated were collated and analyzed from January 1998-December 2007 at the Oral Microbiology Laboratory, Glasgow Dental Hospital. RESULTS: There were 11,312 specimens submitted to the laboratory over the study time period. S aureus was isolated from 1,986 specimens (18%). Of these, 1,782 (90%) were methicillin-sensitive S aureus (MSSA), and 204 (10%) were methicillin-resistant S aureus (MRSA). The most common specimen type from which MSSA was isolated was an oral rinse, whereas for MRSA this was a tongue swab. Most of the MRSA isolates were EMRSA-15 or EMRSA-16 lineage. CONCLUSION: These findings suggest that S aureus continues to be a frequent isolate in the oral cavity and perioral region. The oral cavity should be considered a source of S aureus in terms of cross-infection and dissemination to other body sites. The role of S aureus in the pathogenesis of certain oral diseases should also be considered as part of a differential diagnosis.
Authors: Karolina Niska; Narcyz Knap; Anna Kędzia; Maciej Jaskiewicz; Wojciech Kamysz; Iwona Inkielewicz-Stepniak Journal: Int J Med Sci Date: 2016-09-27 Impact factor: 3.738
Authors: Eugene P Magennis; Nora Francini; Francesca Mastrotto; Rosa Catania; Martin Redhead; Francisco Fernandez-Trillo; David Bradshaw; David Churchley; Klaus Winzer; Cameron Alexander; Giuseppe Mantovani Journal: PLoS One Date: 2017-07-03 Impact factor: 3.240