Literature DB >> 25562057

Monitored viral load: a measure of HIV treatment outcomes in an outpatient setting in Rhode Island.

Francine Touzard Romo1, Fizza S Gillani2, Peter Ackerman2, Aadia Rana2, Erna M Kojic2, Curt G Beckwith2.   

Abstract

Community viral load measurements have been postulated to be a population-based biomarker of HIV disease. We propose the use of the monitored community viral load (mCVL) as an aggregate measure of viral load among persons receiving HIV care with available HIV-1 plasma viral loads and applied it to our clinic population from 2003-2010. We demonstrated a reduction in mCVL from 16,589 copies/ml to 11,992 copies/ml that correlated with a rising rate of antiretroviral use and HIV viral suppression; however, differences among risk populations were observed. The mCVL is a useful measure of HIV burden among patients in-care; it may reflect the HIV transmission risk in the community and help target preventive interventions.

Entities:  

Keywords:  Antiretroviral therapy; Community viral load; HIV; Rhode Island

Mesh:

Substances:

Year:  2014        PMID: 25562057      PMCID: PMC4357270     

Source DB:  PubMed          Journal:  R I Med J (2013)        ISSN: 0363-7913


  15 in total

1.  Use of the community viral load as a population-based biomarker of HIV burden.

Authors:  Amanda D Castel; Montina Befus; Sarah Willis; Angelique Griffin; Tiffany West; Shannon Hader; Alan E Greenberg
Journal:  AIDS       Date:  2012-01-28       Impact factor: 4.177

2.  Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group.

Authors:  T C Quinn; M J Wawer; N Sewankambo; D Serwadda; C Li; F Wabwire-Mangen; M O Meehan; T Lutalo; R H Gray
Journal:  N Engl J Med       Date:  2000-03-30       Impact factor: 91.245

3.  Association between paired plasma and cervicovaginal lavage fluid HIV-1 RNA levels during 36 months.

Authors:  Susan Cu-Uvin; Brad Snyder; Joseph I Harwell; Joseph Hogan; Carla Chibwesha; Dawn Hanley; Jessica Ingersoll; Jaclynn Kurpewski; Kenneth H Mayer; Angela M Caliendo
Journal:  J Acquir Immune Defic Syndr       Date:  2006-08-15       Impact factor: 3.731

Review 4.  The spectrum of engagement in HIV care and its relevance to test-and-treat strategies for prevention of HIV infection.

Authors:  Edward M Gardner; Margaret P McLees; John F Steiner; Carlos Del Rio; William J Burman
Journal:  Clin Infect Dis       Date:  2011-03-15       Impact factor: 9.079

Review 5.  The state of engagement in HIV care in the United States: from cascade to continuum to control.

Authors:  Michael J Mugavero; K Rivet Amico; Tim Horn; Melanie A Thompson
Journal:  Clin Infect Dis       Date:  2013-06-23       Impact factor: 9.079

6.  Dramatic decline in the HIV-1 RNA level over calendar time in a large urban HIV practice.

Authors:  Richard D Moore; John G Bartlett
Journal:  Clin Infect Dis       Date:  2011-08-14       Impact factor: 9.079

7.  Community viral load as a measure for assessment of HIV treatment as prevention.

Authors:  William C Miller; Kimberly A Powers; M Kumi Smith; Myron S Cohen
Journal:  Lancet Infect Dis       Date:  2013-03-25       Impact factor: 25.071

8.  U.S. trends in antiretroviral therapy use, HIV RNA plasma viral loads, and CD4 T-lymphocyte cell counts among HIV-infected persons, 2000 to 2008.

Authors:  Keri N Althoff; Kate Buchacz; H Irene Hall; Jinbing Zhang; David B Hanna; Peter Rebeiro; Stephen J Gange; Richard D Moore; Mari M Kitahata; Kelly A Gebo; Jeffrey Martin; Amy C Justice; Michael A Horberg; Robert S Hogg; Timothy R Sterling; Angela Cescon; Marina B Klein; Jennifer E Thorne; Heidi M Crane; Michael J Mugavero; Sonia Napravnik; Gregory D Kirk; Lisa P Jacobson; John T Brooks
Journal:  Ann Intern Med       Date:  2012-09-04       Impact factor: 25.391

9.  A mathematical model of comprehensive test-and-treat services and HIV incidence among men who have sex with men in the United States.

Authors:  Stephen W Sorensen; Stephanie L Sansom; John T Brooks; Gary Marks; Elizabeth M Begier; Kate Buchacz; Elizabeth A Dinenno; Jonathan H Mermin; Peter H Kilmarx
Journal:  PLoS One       Date:  2012-02-10       Impact factor: 3.240

Review 10.  HIV treatment as prevention: the utility and limitations of ecological observation.

Authors:  M Kumi Smith; Kimberly A Powers; Kathryn E Muessig; William C Miller; Myron S Cohen
Journal:  PLoS Med       Date:  2012-07-10       Impact factor: 11.069

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  6 in total

1.  Community viral load and hepatitis C virus infection: Community viral load measures to aid public health treatment efforts and program evaluation.

Authors:  Ashly E Jordan; David C Perlman; Charles M Cleland; Katarzyna Wyka; Bruce R Schackman; Denis Nash
Journal:  J Clin Virol       Date:  2020-01-27       Impact factor: 3.168

2.  Statewide Evaluation of New HIV Diagnoses in Rhode Island: Implications for Prevention.

Authors:  Philip A Chan; Madeline C Montgomery; Jennifer Rose; Alec Tributino; Christina Crowley; Martha M Medina; Rupa Patel; Kenneth Mayer; Rami Kantor; Amy S Nunn
Journal:  Public Health Rep       Date:  2018-06-06       Impact factor: 2.792

3.  Open Trial of an Acceptance-Based Behavior Therapy Intervention to Engage Newly Diagnosed HIV Patients in Care: Rationale and Evidence of Feasibility and Acceptability.

Authors:  Ethan Moitra; Philip A Chan; Michael D Stein
Journal:  Behav Modif       Date:  2015-06-25

4.  Improving the impact of HIV pre-exposure prophylaxis implementation in small urban centers among men who have sex with men: An agent-based modelling study.

Authors:  Jason R Gantenberg; Maximilian King; Madeline C Montgomery; Omar Galárraga; Mattia Prosperi; Philip A Chan; Brandon D L Marshall
Journal:  PLoS One       Date:  2018-07-09       Impact factor: 3.240

5.  Reduction in HIV community viral loads following the implementation of a "Treatment as Prevention" strategy over 2 years at a population-level among men who have sex with men in Hangzhou, China.

Authors:  Lin He; Jiezhe Yang; Qiaoqin Ma; Jiafeng Zhang; Yun Xu; Yan Xia; Wanjun Chen; Hui Wang; Jinlei Zheng; Jun Jiang; Yan Luo; Ke Xu; Xingliang Zhang; Shichang Xia; Xiaohong Pan
Journal:  BMC Infect Dis       Date:  2018-02-01       Impact factor: 3.090

6.  Effects of HIV on metabolic and biological pathways of CD4+ T lymphocytes.

Authors:  Yanli Ma; Wenge Zhao; Changhe Shi; Ning Wang; Tianli Fan
Journal:  Exp Ther Med       Date:  2018-01-12       Impact factor: 2.447

  6 in total

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