GLP-1: a mediator of the beneficial metabolic effects of bariatric surgery?

There has been increasing interest in the role that gut hormones may play in contributing to the physiological changes produced by certain bariatric procedures, such as Roux-en-Y gastric bypass and sleeve gastrectomy. Here, we review the evidence implicating one such gut hormone, glucagon-like peptide-1, as a mediator of the metabolic benefits of these two procedures. ©2015 Int. Union Physiol. Sci./Am. Physiol. Soc.