Literature DB >> 2555704

Definition of an Ets1 protein domain required for nuclear localization in cells and DNA-binding activity in vitro.

K E Boulukos1, P Pognonec, B Rabault, A Begue, J Ghysdael.   

Abstract

Ets1 and Ets2 are nuclear phosphoproteins which bind to DNA in vitro and share two domains of strong identity. Deletion analyses of each of these conserved regions in Ets1 demonstrated that integrity of the carboxy-terminal domain, also conserved in the more distantly related elk and erg gene products, is essential for both nuclear targeting and DNA-binding activity in vitro.

Entities:  

Mesh:

Substances:

Year:  1989        PMID: 2555704      PMCID: PMC363744          DOI: 10.1128/mcb.9.12.5718-5721.1989

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN: 0270-7306            Impact factor:   4.272


  23 in total

1.  Nuclear location signals in polyoma virus large-T.

Authors:  W D Richardson; B L Roberts; A E Smith
Journal:  Cell       Date:  1986-01-17       Impact factor: 41.582

2.  Identification and preferential expression in thymic and bursal lymphocytes of a c-ets oncogene-encoded Mr 54,000 cytoplasmic protein.

Authors:  J Ghysdael; A Gegonne; P Pognonec; D Dernis; D Leprince; D Stehelin
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205

3.  The proto-oncogene c-ets is preferentially expressed in lymphoid cells.

Authors:  J H Chen
Journal:  Mol Cell Biol       Date:  1985-11       Impact factor: 4.272

4.  Multiple domains for the chicken cellular sequences homologous to the v-ets oncogene of the E26 retrovirus.

Authors:  A Gegonne; D Leprince; M Duterque-Coquillaud; B Vandenbunder; A Flourens; J Ghysdael; B Debuire; D Stehelin
Journal:  Mol Cell Biol       Date:  1987-02       Impact factor: 4.272

5.  The erg gene: a human gene related to the ets oncogene.

Authors:  E S Reddy; V N Rao; T S Papas
Journal:  Proc Natl Acad Sci U S A       Date:  1987-09       Impact factor: 11.205

6.  Temporal and tissue-specific expression of mouse ets genes.

Authors:  N K Bhat; R J Fisher; S Fujiwara; R Ascione; T S Papas
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

7.  Molecular organization of the chicken ets locus.

Authors:  D K Watson; M J McWilliams; T S Papas
Journal:  Virology       Date:  1988-05       Impact factor: 3.616

8.  erg, a human ets-related gene on chromosome 21: alternative splicing, polyadenylation, and translation.

Authors:  V N Rao; T S Papas; E S Reddy
Journal:  Science       Date:  1987-08-07       Impact factor: 47.728

9.  Plasmids for the cloning and expression of full-length double-stranded cDNAs under control of the SV40 early or late gene promoter.

Authors:  R Breathnach; B A Harris
Journal:  Nucleic Acids Res       Date:  1983-10-25       Impact factor: 16.971

10.  Identification in chicken macrophages of a set of proteins related to, but distinct from, the chicken cellular c-ets-encoded protein p54c-ets.

Authors:  J Ghysdael; A Gegonne; P Pognonec; K Boulukos; D Leprince; D Dernis; C Lagrou; D Stehelin
Journal:  EMBO J       Date:  1986-09       Impact factor: 11.598

View more
  39 in total

1.  The MN1-TEL fusion protein, encoded by the translocation (12;22)(p13;q11) in myeloid leukemia, is a transcription factor with transforming activity.

Authors:  A Buijs; L van Rompaey; A C Molijn; J N Davis; A C Vertegaal; M D Potter; C Adams; S van Baal; E C Zwarthoff; M F Roussel; G C Grosveld
Journal:  Mol Cell Biol       Date:  2000-12       Impact factor: 4.272

2.  Functional analysis of the transcription factor ER71 and its activation of the matrix metalloproteinase-1 promoter.

Authors:  Luciano De Haro; Ralf Janknecht
Journal:  Nucleic Acids Res       Date:  2002-07-01       Impact factor: 16.971

3.  ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression.

Authors:  Lionel Le Gallic; Laura Virgilio; Philip Cohen; Benoit Biteau; George Mavrothalassitis
Journal:  Mol Cell Biol       Date:  2004-02       Impact factor: 4.272

4.  The ETS transcription factor ESE-1 transforms MCF-12A human mammary epithelial cells via a novel cytoplasmic mechanism.

Authors:  Jason D Prescott; Karen S N Koto; Meenakshi Singh; Arthur Gutierrez-Hartmann
Journal:  Mol Cell Biol       Date:  2004-06       Impact factor: 4.272

5.  ETS-1 protein regulates vascular endothelial growth factor-induced matrix metalloproteinase-9 and matrix metalloproteinase-13 expression in human ovarian carcinoma cell line SKOV-3.

Authors:  Sonali Ghosh; Moitri Basu; Sib Sankar Roy
Journal:  J Biol Chem       Date:  2012-01-23       Impact factor: 5.157

6.  A domain shared by the Polycomb group proteins Scm and ph mediates heterotypic and homotypic interactions.

Authors:  A J Peterson; M Kyba; D Bornemann; K Morgan; H W Brock; J Simon
Journal:  Mol Cell Biol       Date:  1997-11       Impact factor: 4.272

7.  Sequence-specific interaction of the Ets1 protein with the long terminal repeat of the human T-lymphotropic virus type I.

Authors:  S D Gitlin; R Bosselut; A Gégonne; J Ghysdael; J N Brady
Journal:  J Virol       Date:  1991-10       Impact factor: 5.103

8.  The transcription factor E26 transformation-specific sequence-1 mediates neointima formation in arteriovenous fistula.

Authors:  Wenguang Feng; Phillip Chumley; Michael Allon; James George; David W Scott; Rakesh P Patel; Silvio Litovsky; Edgar A Jaimes
Journal:  J Am Soc Nephrol       Date:  2013-11-07       Impact factor: 10.121

Review 9.  Nuclear localization signals overlap DNA- or RNA-binding domains in nucleic acid-binding proteins.

Authors:  E C LaCasse; Y A Lefebvre
Journal:  Nucleic Acids Res       Date:  1995-05-25       Impact factor: 16.971

Review 10.  The oncogene ERG: a key factor in prostate cancer.

Authors:  P Adamo; M R Ladomery
Journal:  Oncogene       Date:  2015-04-27       Impact factor: 9.867

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.