Literature DB >> 25552780

GENERAL THEORY FOR INTERACTIONS IN SUFFICIENT CAUSE MODELS WITH DICHOTOMOUS EXPOSURES.

Tyler J VanderWeele1, Thomas S Richardson2.   

Abstract

The sufficient-component cause framework assumes the existence of sets of sufficient causes that bring about an event. For a binary outcome and an arbitrary number of binary causes any set of potential outcomes can be replicated by positing a set of sufficient causes; typically this representation is not unique. A sufficient cause interaction is said to be present if within all representations there exists a sufficient cause in which two or more particular causes are all present. A singular interaction is said to be present if for some subset of individuals there is a unique minimal sufficient cause. Empirical and counterfactual conditions are given for sufficient cause interactions and singular interactions between an arbitrary number of causes. Conditions are given for cases in which none, some or all of a given set of causes affect the outcome monotonically. The relations between these results, interactions in linear statistical models and Pearl's probability of causation are discussed.

Entities:  

Keywords:  causal inference; counterfactual; epistasis; interaction include keywords that are in title; potential outcomes; synergism

Year:  2012        PMID: 25552780      PMCID: PMC4278668          DOI: 10.1214/12-aos1019

Source DB:  PubMed          Journal:  Ann Stat        ISSN: 0090-5364            Impact factor:   4.028


  15 in total

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Journal:  Hum Mol Genet       Date:  2002-10-01       Impact factor: 6.150

3.  From counterfactuals to sufficient component causes and vice versa.

Authors:  Tyler J VanderWeele; Miguel A Hernán
Journal:  Eur J Epidemiol       Date:  2006       Impact factor: 8.082

4.  On the relationship of sufficient component cause models with potential outcome (counterfactual) models.

Authors:  W Dana Flanders
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5.  Causes.

Authors:  K J Rothman
Journal:  Am J Epidemiol       Date:  1976-12       Impact factor: 4.897

6.  Epistatic interactions.

Authors:  Tyler J VanderWeele
Journal:  Stat Appl Genet Mol Biol       Date:  2010-01-06

7.  Invariants and noninvariants in the concept of interdependent effects.

Authors:  S Greenland; C Poole
Journal:  Scand J Work Environ Health       Date:  1988-04       Impact factor: 5.024

8.  Interaction between discrete causes.

Authors:  J S Koopman
Journal:  Am J Epidemiol       Date:  1981-06       Impact factor: 4.897

9.  The role of N-acetylation polymorphisms in smoking-associated bladder cancer: evidence of a gene-gene-exposure three-way interaction.

Authors:  J A Taylor; D M Umbach; E Stephens; T Castranio; D Paulson; C Robertson; J L Mohler; D A Bell
Journal:  Cancer Res       Date:  1998-08-15       Impact factor: 12.701

Review 10.  Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems.

Authors:  Patrick C Phillips
Journal:  Nat Rev Genet       Date:  2008-11       Impact factor: 53.242

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  3 in total

1.  A mapping between interactions and interference: implications for vaccine trials.

Authors:  Tyler J VanderWeele; Jan P Vandenbroucke; Eric J Tchetgen Tchetgen; James M Robins
Journal:  Epidemiology       Date:  2012-03       Impact factor: 4.822

2.  Additive interaction in the presence of a mismeasured outcome.

Authors:  Zhichao Jiang; Tyler J VanderWeele
Journal:  Am J Epidemiol       Date:  2014-12-16       Impact factor: 4.897

3.  Invited Commentary: The Continuing Need for the Sufficient Cause Model Today.

Authors:  Tyler J VanderWeele
Journal:  Am J Epidemiol       Date:  2017-06-01       Impact factor: 4.897

  3 in total

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