Literature DB >> 25544727

Microfluidic platform towards point-of-care diagnostics in infectious diseases.

Wentao Su1, Xinghua Gao2, Lei Jiang1, Jianhua Qin3.   

Abstract

Rapid and timely diagnosis of infectious diseases is a critical determinant of clinical outcomes and general public health. For the detection of various pathogens, microfluidics-based platforms offer many advantages, including speed, cost, portability, high throughput, and automation. This review provides an overview of the recent advances in microfluidic technologies for point-of-care (POC) diagnostics for infectious diseases. The key aspects of such technologies for the development of a fully integrated POC platform are introduced, including sample preparation, on-chip nucleic acid analysis and immunoassay, and system integration/automation. The current challenges to practical implementation of this technology are discussed together with future perspectives.
Copyright © 2014 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Immunoassay; Infectious disease; Microfluidic; Nucleic acid analysis; Point-of-care testing

Mesh：

Year:  2014        PMID： 25544727     DOI： 10.1016/j.chroma.2014.12.041

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN： 0021-9673            Impact factor:   4.759


  38 in total

Review 1.  Biomarker detection for disease diagnosis using cost-effective microfluidic platforms.

Authors:  Sharma T Sanjay; Guanglei Fu; Maowei Dou; Feng Xu; Rutao Liu; Hao Qi; XiuJun Li
Journal:  Analyst       Date:  2015-11-07       Impact factor: 4.616

2.  Continuous monitoring of adenosine and its metabolites using microdialysis coupled to microchip electrophoresis with amperometric detection.

Authors:  Shamal M Gunawardhana; Susan M Lunte
Journal:  Anal Methods       Date:  2018-07-13       Impact factor: 2.896

3.  Microfluidic tools for probing micro-culprits: Opportunities and challenges in microfluidic diagnostics.

Authors:  Su Bin Lim; Nishanth Venugopal Menon; Chwee Teck Lim
Journal:  EMBO Rep       Date:  2020-01-29       Impact factor: 8.807

4.  On-Chip Spyhole Nanoelectrospray Ionization Mass Spectrometry for Sensitive Biomarker Detection in Small Volumes.

Authors:  Xiaoqin Zhong; Liang Qiao; Géraldine Stauffer; Baohong Liu; Hubert H Girault
Journal:  J Am Soc Mass Spectrom       Date:  2018-03-20       Impact factor: 3.109

5.  Multi-parameter analysis using photovoltaic cell-based optofluidic cytometer.

Authors:  Chien-Shun Yan; Yao-Nan Wang
Journal:  Biomed Opt Express       Date:  2016-08-22       Impact factor: 3.732

6.  On-chip stool liquefaction via acoustofluidics.

Authors:  Shuaiguo Zhao; Weihua He; Zhehan Ma; Peiyao Liu; Po-Hsun Huang; Hunter Bachman; Lin Wang; Shujie Yang; Zhenhua Tian; Zeyu Wang; Yuyang Gu; Zhemiao Xie; Tony Jun Huang
Journal:  Lab Chip       Date:  2019-03-13       Impact factor: 6.799

7.  Label-Free Detection and Discrimination of Bacterial Pathogens Based on Hemin Recognition.

Authors:  Thora R Maltais; Avijit K Adak; Waleed Younis; Mohamed N Seleem; Alexander Wei
Journal:  Bioconjug Chem       Date:  2016-07-01       Impact factor: 4.774

8.  Integrated, DC voltage-driven nucleic acid diagnostic platform for real sample analysis: Detection of oral cancer.

Authors:  Zdenek Slouka; Satyajyoti Senapati; Sunny Shah; Robin Lawler; Zonggao Shi; M Sharon Stack; Hsueh-Chia Chang
Journal:  Talanta       Date:  2015-05-06       Impact factor: 6.057

Review 9.  A Comparison of Optical, Electrochemical, Magnetic, and Colorimetric Point-of-Care Biosensors for Infectious Disease Diagnosis.

Authors:  Oleksandra Pashchenko; Tyler Shelby; Tuhina Banerjee; Santimukul Santra
Journal:  ACS Infect Dis       Date:  2018-06-18       Impact factor: 5.084

Review 10.  Point-of-care diagnosis of periodontitis using saliva: technically feasible but still a challenge.

Authors:  Suk Ji; Youngnim Choi
Journal:  Front Cell Infect Microbiol       Date:  2015-09-03       Impact factor: 5.293
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