Literature DB >> 25537257

Automated pancreatic cyst screening using natural language processing: a new tool in the early detection of pancreatic cancer.

Alexandra M Roch1, Saeed Mehrabi, Anand Krishnan, Heidi E Schmidt, Joseph Kesterson, Chris Beesley, Paul R Dexter, Mathew Palakal, C Max Schmidt.   

Abstract

INTRODUCTION: As many as 3% of computed tomography (CT) scans detect pancreatic cysts. Because pancreatic cysts are incidental, ubiquitous and poorly understood, follow-up is often not performed. Pancreatic cysts may have a significant malignant potential and their identification represents a 'window of opportunity' for the early detection of pancreatic cancer. The purpose of this study was to implement an automated Natural Language Processing (NLP)-based pancreatic cyst identification system.
METHOD: A multidisciplinary team was assembled. NLP-based identification algorithms were developed based on key words commonly used by physicians to describe pancreatic cysts and programmed for automated search of electronic medical records. A pilot study was conducted prospectively in a single institution.
RESULTS: From March to September 2013, 566,233 reports belonging to 50,669 patients were analysed. The mean number of patients reported with a pancreatic cyst was 88/month (range 78-98). The mean sensitivity and specificity were 99.9% and 98.8%, respectively.
CONCLUSION: NLP is an effective tool to automatically identify patients with pancreatic cysts based on electronic medical records (EMR). This highly accurate system can help capture patients 'at-risk' of pancreatic cancer in a registry.
© 2014 International Hepato-Pancreato-Biliary Association.

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Year:  2014        PMID: 25537257      PMCID: PMC4402056          DOI: 10.1111/hpb.12375

Source DB:  PubMed          Journal:  HPB (Oxford)        ISSN: 1365-182X            Impact factor:   3.647


  20 in total

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Journal:  Pancreatology       Date:  2012-04-16       Impact factor: 3.996

Review 3.  Natural language processing: an introduction.

Authors:  Prakash M Nadkarni; Lucila Ohno-Machado; Wendy W Chapman
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4.  Characterization of cystic tumors of the pancreas: CT accuracy.

Authors:  C Procacci; C Biasiutti; G Carbognin; S Accordini; E Bicego; A Guarise; E Spoto; I A Andreis; R De Marco; A J Megibow
Journal:  J Comput Assist Tomogr       Date:  1999 Nov-Dec       Impact factor: 1.826

5.  Pancreatic cysts: depiction on single-shot fast spin-echo MR images.

Authors:  Xiao-Ming Zhang; Donald G Mitchell; Masako Dohke; George A Holland; Laurence Parker
Journal:  Radiology       Date:  2002-05       Impact factor: 11.105

6.  Analysis of small cystic lesions of the pancreas.

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Review 7.  Systematic review of carbohydrate antigen (CA 19-9) as a biochemical marker in the diagnosis of pancreatic cancer.

Authors:  K S Goonetilleke; A K Siriwardena
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Review 9.  Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative.

Authors:  Patrick M Bossuyt; Johannes B Reitsma; David E Bruns; Constantine A Gatsonis; Paul P Glasziou; Les M Irwig; Jeroen G Lijmer; David Moher; Drummond Rennie; Henrica C W de Vet
Journal:  BMJ       Date:  2003-01-04

10.  An efficient pancreatic cyst identification methodology using natural language processing.

Authors:  Saeed Mehrabi; C Max Schmidt; Joshua A Waters; Chris Beesley; Anand Krishnan; Joe Kesterson; Paul Dexter; Mohammed A Al-Haddad; William M Tierney; Mathew Palakal
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  8 in total

1.  DEEPEN: A negation detection system for clinical text incorporating dependency relation into NegEx.

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Review 3.  Clinical information extraction applications: A literature review.

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Journal:  J Biomed Inform       Date:  2017-11-21       Impact factor: 6.317

4.  Identification of Patients with Family History of Pancreatic Cancer--Investigation of an NLP System Portability.

Authors:  Saeed Mehrabi; Anand Krishnan; Alexandra M Roch; Heidi Schmidt; DingCheng Li; Joe Kesterson; Chris Beesley; Paul Dexter; Max Schmidt; Mathew Palakal; Hongfang Liu
Journal:  Stud Health Technol Inform       Date:  2015

Review 5.  Extracting information from the text of electronic medical records to improve case detection: a systematic review.

Authors:  Elizabeth Ford; John A Carroll; Helen E Smith; Donia Scott; Jackie A Cassell
Journal:  J Am Med Inform Assoc       Date:  2016-02-05       Impact factor: 4.497

Review 6.  Assessment of Electronic Health Record for Cancer Research and Patient Care Through a Scoping Review of Cancer Natural Language Processing.

Authors:  Liwei Wang; Sunyang Fu; Andrew Wen; Xiaoyang Ruan; Huan He; Sijia Liu; Sungrim Moon; Michelle Mai; Irbaz B Riaz; Nan Wang; Ping Yang; Hua Xu; Jeremy L Warner; Hongfang Liu
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7.  Identification of Individuals at Increased Risk for Pancreatic Cancer in a Community-Based Cohort of Patients With Suspected Chronic Pancreatitis.

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Review 8.  The Role of Artificial Intelligence in Early Cancer Diagnosis.

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  8 in total

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