Literature DB >> 25534912

Motor neuron disease in 2014. Biomarkers for ALS--in search of the Promised Land.

Adriano Chiò1, Bryan J Traynor2.   

Abstract

The past year has seen some extraordinary activity in clinical amyotrophic lateral sclerosis (ALS) research. Two trials were completed, with negative results, but the discovery of novel ALS-associated genes, and body fluid and imaging biomarkers warrants cautious optimism. Here, we provide a snapshot of some of the main findings in 2014.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25534912      PMCID： PMC5185468          DOI： 10.1038/nrneurol.2014.250

Source DB:  PubMed          Journal:  Nat Rev Neurol        ISSN： 1759-4758            Impact factor:   42.937


  10 in total

1.  A phase II-III trial of olesoxime in subjects with amyotrophic lateral sclerosis.

Authors:  T Lenglet; L Lacomblez; J L Abitbol; A Ludolph; J S Mora; W Robberecht; P J Shaw; R M Pruss; V Cuvier; V Meininger
Journal:  Eur J Neurol       Date:  2014-01-21       Impact factor: 6.089

2.  Value of 18fluorodeoxyglucose-positron-emission tomography in amyotrophic lateral sclerosis: a prospective study.

Authors:  Koen Van Laere; Annelies Vanhee; Jolien Verschueren; Liesbeth De Coster; An Driesen; Patrick Dupont; Wim Robberecht; Philip Van Damme
Journal:  JAMA Neurol       Date:  2014-05       Impact factor: 18.302

3.  Safety and efficacy of ceftriaxone for amyotrophic lateral sclerosis: a multi-stage, randomised, double-blind, placebo-controlled trial.

Authors:  Merit E Cudkowicz; Sarah Titus; Marianne Kearney; Hong Yu; Alexander Sherman; David Schoenfeld; Douglas Hayden; Amy Shui; Benjamin Brooks; Robin Conwit; Donna Felsenstein; David J Greenblatt; Myles Keroack; John T Kissel; Robert Miller; Jeffrey Rosenfeld; Jeffrey D Rothstein; Ericka Simpson; Nina Tolkoff-Rubin; Lorne Zinman; Jeremy M Shefner
Journal:  Lancet Neurol       Date:  2014-10-05       Impact factor: 44.182

4.  Phosphorylated tau as a candidate biomarker for amyotrophic lateral sclerosis.

Authors:  Murray Grossman; Lauren Elman; Leo McCluskey; Corey T McMillan; Ashley Boller; John Powers; Katya Rascovsky; William Hu; Les Shaw; David J Irwin; Virginia M-Y Lee; John Q Trojanowski
Journal:  JAMA Neurol       Date:  2014-04       Impact factor: 18.302

5.  Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS.

Authors:  Bradley N Smith; Nicola Ticozzi; Claudia Fallini; Athina Soragia Gkazi; Simon Topp; Kevin P Kenna; Emma L Scotter; Jason Kost; Pamela Keagle; Jack W Miller; Daniela Calini; Caroline Vance; Eric W Danielson; Claire Troakes; Cinzia Tiloca; Safa Al-Sarraj; Elizabeth A Lewis; Andrew King; Claudia Colombrita; Viviana Pensato; Barbara Castellotti; Jacqueline de Belleroche; Frank Baas; Anneloor L M A ten Asbroek; Peter C Sapp; Diane McKenna-Yasek; Russell L McLaughlin; Meraida Polak; Seneshaw Asress; Jesús Esteban-Pérez; José Luis Muñoz-Blanco; Michael Simpson; Wouter van Rheenen; Frank P Diekstra; Giuseppe Lauria; Stefano Duga; Stefania Corti; Cristina Cereda; Lucia Corrado; Gianni Sorarù; Karen E Morrison; Kelly L Williams; Garth A Nicholson; Ian P Blair; Patrick A Dion; Claire S Leblond; Guy A Rouleau; Orla Hardiman; Jan H Veldink; Leonard H van den Berg; Ammar Al-Chalabi; Hardev Pall; Pamela J Shaw; Martin R Turner; Kevin Talbot; Franco Taroni; Alberto García-Redondo; Zheyang Wu; Jonathan D Glass; Cinzia Gellera; Antonia Ratti; Robert H Brown; Vincenzo Silani; Christopher E Shaw; John E Landers
Journal:  Neuron       Date:  2014-10-22       Impact factor: 17.173

6.  Increased neurofilament light chain blood levels in neurodegenerative neurological diseases.

Authors:  Johanna Gaiottino; Niklas Norgren; Ruth Dobson; Joanne Topping; Ahuva Nissim; Andrea Malaspina; Jonathan P Bestwick; Andreas U Monsch; Axel Regeniter; Raija L Lindberg; Ludwig Kappos; David Leppert; Axel Petzold; Gavin Giovannoni; Jens Kuhle
Journal:  PLoS One       Date:  2013-09-20       Impact factor: 3.240

7.  Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis.

Authors:  Janel O Johnson; Erik P Pioro; Ashley Boehringer; Ruth Chia; Gabriella Restagno; Mario Sabatelli; Robert Bowser; Adriano Chiò; Bryan J Traynor; Howard Feit; Alan E Renton; Hannah A Pliner; Yevgeniya Abramzon; Giuseppe Marangi; Brett J Winborn; J Raphael Gibbs; Michael A Nalls; Sarah Morgan; Maryam Shoai; John Hardy; Alan Pittman; Richard W Orrell; Andrea Malaspina; Katie C Sidle; Pietro Fratta; Matthew B Harms; Robert H Baloh; Alan Pestronk; Conrad C Weihl; Ekaterina Rogaeva; Lorne Zinman; Vivian E Drory; Giuseppe Borghero; Gabriele Mora; Andrea Calvo; Jeffrey D Rothstein; Carsten Drepper; Michael Sendtner; Andrew B Singleton; J Paul Taylor; Mark R Cookson
Journal:  Nat Neurosci       Date:  2014-03-30       Impact factor: 24.884

8.  Multimodal MRI as a diagnostic biomarker for amyotrophic lateral sclerosis.

Authors:  Bradley R Foerster; Ruth C Carlos; Ben A Dwamena; Brian C Callaghan; Myria Petrou; Richard A E Edden; Mona A Mohamed; Robert C Welsh; Peter B Barker; Eva L Feldman; Martin G Pomper
Journal:  Ann Clin Transl Neurol       Date:  2014-01-13       Impact factor: 4.511

9.  Functional pattern of brain FDG-PET in amyotrophic lateral sclerosis.

Authors:  Marco Pagani; Adriano Chiò; Maria Consuelo Valentini; Johanna Öberg; Flavio Nobili; Andrea Calvo; Cristina Moglia; Davide Bertuzzo; Silvia Morbelli; Fabrizio De Carli; Piercarlo Fania; Angelina Cistaro
Journal:  Neurology       Date:  2014-08-13       Impact factor: 9.910

10.  A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement.

Authors:  Sylvie Bannwarth; Samira Ait-El-Mkadem; Annabelle Chaussenot; Emmanuelle C Genin; Sandra Lacas-Gervais; Konstantina Fragaki; Laetitia Berg-Alonso; Yusuke Kageyama; Valérie Serre; David G Moore; Annie Verschueren; Cécile Rouzier; Isabelle Le Ber; Gaëlle Augé; Charlotte Cochaud; Françoise Lespinasse; Karine N'Guyen; Anne de Septenville; Alexis Brice; Patrick Yu-Wai-Man; Hiromi Sesaki; Jean Pouget; Véronique Paquis-Flucklinger
Journal:  Brain       Date:  2014-06-16       Impact factor: 13.501
  10 in total
  8 in total

1.  Epidemiology of amyotrophic lateral sclerosis in Southern Germany.

Authors:  Angela Rosenbohm; Raphael S Peter; Siegfried Erhardt; Dorothée Lulé; Dietrich Rothenbacher; Albert C Ludolph; Gabriele Nagel
Journal:  J Neurol       Date:  2017-02-20       Impact factor: 4.849

Review 2.  The path to biomarker-based diagnostic criteria for the spectrum of neurodegenerative diseases.

Authors:  Filippo Baldacci; Sonia Mazzucchi; Alessandra Della Vecchia; Linda Giampietri; Nicola Giannini; Maya Koronyo-Hamaoui; Roberto Ceravolo; Gabriele Siciliano; Ubaldo Bonuccelli; Fanny M Elahi; Andrea Vergallo; Simone Lista; Filippo Sean Giorgi; Harald Hampel
Journal:  Expert Rev Mol Diagn       Date:  2020-02-27       Impact factor: 5.225

3.  Acoustic reflex patterns in amyotrophic lateral sclerosis.

Authors:  Andrea Canale; Roberto Albera; Michelangelo Lacilla; Antonio Canosa; Andrea Albera; Francesca Sacco; Adriano Chiò; Andrea Calvo
Journal:  Eur Arch Otorhinolaryngol       Date:  2016-08-30       Impact factor: 2.503

Review 4.  Novel genes associated with amyotrophic lateral sclerosis: diagnostic and clinical implications.

Authors:  Ruth Chia; Adriano Chiò; Bryan J Traynor
Journal:  Lancet Neurol       Date:  2017-11-16       Impact factor: 44.182

5.  Imaging Neurochemistry and Brain Structure Tracks Clinical Decline and Mechanisms of ALS in Patients.

Authors:  Ovidiu C Andronesi; Katharine Nicholson; Kourosh Jafari-Khouzani; Wolfgang Bogner; Jing Wang; James Chan; Eric A Macklin; Mark Levine-Weinberg; Christopher Breen; Michael A Schwarzschild; Merit Cudkowicz; Bruce R Rosen; Sabrina Paganoni; Eva-Maria Ratai
Journal:  Front Neurol       Date:  2020-12-03       Impact factor: 4.003

6.  Analysis of routine blood parameters in patients with amyotrophic lateral sclerosis and evaluation of a possible correlation with disease progression-a multicenter study.

Authors:  Nora Hertel; Magdalena Kuzma-Kozakiewicz; Marta Gromicho; Julian Grosskreutz; Mamede de Carvalho; Hilmi Uysal; Reinhard Dengler; Susanne Petri; Sonja Körner
Journal:  Front Neurol       Date:  2022-07-27       Impact factor: 4.086

Review 7.  RNA-Targeted Therapies and Amyotrophic Lateral Sclerosis.

Authors:  Stéphane Mathis; Gwendal Le Masson
Journal:  Biomedicines       Date:  2018-01-15

Review 8.  Biomarkers of Spinal and Bulbar Muscle Atrophy (SBMA): A Comprehensive Review.

Authors:  Giorgia Querin; Peter Bede; Veronique Marchand-Pauvert; Pierre-Francois Pradat
Journal:  Front Neurol       Date:  2018-10-10       Impact factor: 4.003
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.