Literature DB >> 25532303

Anticancer agents from diverse natural sources.

Jabeena Khazir, Darren L Riley, Lynne A Pilcher, Pieter De-Maayer, Bilal Ahmad Mir.   

Abstract

This review attempts to portray the discovery and development of anticancer agents/drugs from diverse natural sources. Natural molecules from these natural sources including plants, microbes and marine organisms have been the basis of treatment of human diseases since the ancient times. Compounds derived from nature have been important sources of new drugs and also serve as templates for synthetic modification. Many successful anti-cancer drugs currently in use are naturally derived or their analogues and many more are under clinical trials. This review aims to highlight the invaluable role that natural products have played, and continue to play, in the discovery of anticancer agents.

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Year:  2014        PMID: 25532303

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN: 1555-9475            Impact factor:   0.986


  15 in total

1.  Novel application assigned to toluquinol: inhibition of lymphangiogenesis by interfering with VEGF-C/VEGFR-3 signalling pathway.

Authors:  M García-Caballero; S Blacher; J Paupert; A R Quesada; M A Medina; A Noël
Journal:  Br J Pharmacol       Date:  2016-05-04       Impact factor: 8.739

2.  Sensitization of MDA-MBA231 breast cancer cell to docetaxel by myricetin loaded into biocompatible lipid nanoparticles via sub-G1 cell cycle arrest mechanism.

Authors:  Nazila Fathi Maroufi; Vahid Vahedian; Seyed Ali Miresmaeili Mazrakhondi; Wesam Kooti; Hosein Ajami Khiavy; Roya Bazzaz; Fatemeh Ramezani; Seyed Mohammadbagher Pirouzpanah; Marjan Ghorbani; Maryam Akbarzadeh; Hamed Hajipour; Saeed Ghanbarzadeh; Mehdi Sabzichi
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2019-08-02       Impact factor: 3.000

3.  Color-Coded Super-Resolution Small-Molecule Imaging.

Authors:  Paolo Beuzer; James J La Clair; Hu Cang
Journal:  Chembiochem       Date:  2016-04-26       Impact factor: 3.164

4.  Selective induced apoptosis and cell cycle arrest in MCF7 and LNCap cell lines by skin mucus from round goby (Neogobius melanostomus) and common carp (Cyprinus carpio) through P53 expression.

Authors:  Rashid Alijani Ardeshir; Sara Rastgar; Payam Morakabati; Hoda Mojiri-Forushani; Abdolali Movahedinia; Amir Parviz Salati
Journal:  Cytotechnology       Date:  2020-03-06       Impact factor: 2.058

5.  Targeting miR-21 with Sophocarpine Inhibits Tumor Progression and Reverses Epithelial-Mesenchymal Transition in Head and Neck Cancer.

Authors:  Wei Liu; Beilei Zhang; Guo Chen; Wenjiao Wu; Lin Zhou; Yaru Shi; Qi Zeng; Yanqiu Li; Youwei Sun; Xingming Deng; Fu Wang
Journal:  Mol Ther       Date:  2017-05-30       Impact factor: 11.454

6.  Partially Purified Extracts of Sea Anemone Anemonia viridis Affect the Growth and Viability of Selected Tumour Cell Lines.

Authors:  Matteo Bulati; Alessandra Longo; Tiziana Masullo; Sara Vlah; Carmelo Bennici; Angela Bonura; Monica Salamone; Marcello Tagliavia; Aldo Nicosia; Salvatore Mazzola; Paolo Colombo; Angela Cuttitta
Journal:  Biomed Res Int       Date:  2016-09-20       Impact factor: 3.411

7.  In vitro screening of cytotoxic activity of euphol from Euphorbia tirucalli on a large panel of human cancer-derived cell lines.

Authors:  Viviane Aline Oliveira Silva; Marcela Nunes Rosa; Aline Tansini; Renato J S Oliveira; Olga Martinho; João Paulo Lima; Luiz F Pianowski; Rui M Reis
Journal:  Exp Ther Med       Date:  2018-05-31       Impact factor: 2.447

8.  Neolignans from Nectandra megapotamica (Lauraceae) Display in vitro Cytotoxic Activity and Induce Apoptosis in Leukemia Cells.

Authors:  Vitor Ponci; Carlos R Figueiredo; Mariana H Massaoka; Camyla F de Farias; Alisson L Matsuo; Patricia Sartorelli; João Henrique G Lago
Journal:  Molecules       Date:  2015-07-15       Impact factor: 4.411

9.  Targeted Delivery Prodigiosin to Choriocarcinoma by Peptide-Guided Dendrigraft Poly-l-lysines Nanoparticles.

Authors:  Kai Zhao; Dan Li; Guogang Cheng; Baozhen Zhang; Jinyu Han; Jie Chen; Baobei Wang; Mengxia Li; Tianxia Xiao; Jian Zhang; Dongpo Zhou; Zheng Jin; Xiujun Fan
Journal:  Int J Mol Sci       Date:  2019-11-01       Impact factor: 5.923

10.  The Cyr61 Is a Potential Target for Rotundifuran, a Natural Labdane-Type Diterpene from Vitex trifolia L., to Trigger Apoptosis of Cervical Cancer Cells.

Authors:  Gang Gong; Yu-Li Shen; Hai-Yue Lan; Jin-Mei Jin; Pei An; Li-Jun Zhang; Li-Li Chen; Wei Peng; Xin Luan; Hong Zhang
Journal:  Oxid Med Cell Longev       Date:  2021-05-22       Impact factor: 6.543

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