Literature DB >> 25527561

Hedgehog pathway mutations in T-cell acute lymphoblastic leukemia.

Antonis Dagklis1, Daphnie Pauwels1, Idoya Lahortiga1, Ellen Geerdens1, Emilie Bittoun2, Barbara Cauwelier3, Thomas Tousseyn2, Anne Uyttebroeck4, Johan Maertens5, Gregor Verhoef5, Peter Vandenberghe6, Jan Cools7.   

Abstract

Entities:  

Keywords:  Hedgehog pathway; leukemia; oncogene; signaling

Mesh：

Substances：

Year:  2014        PMID： 25527561      PMCID： PMC4349289          DOI： 10.3324/haematol.2014.119248

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


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  15 in total

1.  Indian hedgehog (Ihh) both promotes and restricts thymocyte differentiation.

Authors:  Susan V Outram; Ariadne L Hager-Theodorides; Divya K Shah; Nicola J Rowbotham; Ekati Drakopoulou; Susan E Ross; Beate Lanske; Johannes T Dessens; Tessa Crompton
Journal:  Blood       Date:  2008-12-23       Impact factor: 22.113

2.  Constitutive activation of the shh-ptc1 pathway by a patched1 mutation identified in BCC.

Authors:  Elizabeth A Barnes; Keely J Heidtman; Daniel J Donoghue
Journal:  Oncogene       Date:  2005-01-27       Impact factor: 9.867

Review 3.  Roles for Hedgehog signaling in adult organ homeostasis and repair.

Authors:  Ralitsa Petrova; Alexandra L Joyner
Journal:  Development       Date:  2014-09       Impact factor: 6.868

4.  The transcription factor Gli3 regulates differentiation of fetal CD4- CD8- double-negative thymocytes.

Authors:  Ariadne L Hager-Theodorides; Johannes T Dessens; Susan V Outram; Tessa Crompton
Journal:  Blood       Date:  2005-04-26       Impact factor: 22.113

Review 5.  Hedgehog beyond medulloblastoma and basal cell carcinoma.

Authors:  Stephan Teglund; Rune Toftgård
Journal:  Biochim Biophys Acta       Date:  2010-01-18

6.  Hedgehog signaling is dispensable for adult hematopoietic stem cell function.

Authors:  Jie Gao; Stephanie Graves; Ute Koch; Suqing Liu; Vladimir Jankovic; Silvia Buonamici; Abdeljabar El Andaloussi; Stephen D Nimer; Barbara L Kee; Russell Taichman; Freddy Radtke; Iannis Aifantis
Journal:  Cell Stem Cell       Date:  2009-06-05       Impact factor: 24.633

7.  Hedgehog regulates smoothened activity by inducing a conformational switch.

Authors:  Yun Zhao; Chao Tong; Jin Jiang
Journal:  Nature       Date:  2007-10-24       Impact factor: 49.962

8.  Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus.

Authors:  Abdeljabar El Andaloussi; Stephanie Graves; Fanyong Meng; Malay Mandal; Mona Mashayekhi; Iannis Aifantis
Journal:  Nat Immunol       Date:  2006-03-05       Impact factor: 25.606

9.  Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine.

Authors:  J Taipale; J K Chen; M K Cooper; B Wang; R K Mann; L Milenkovic; M P Scott; P A Beachy
Journal:  Nature       Date:  2000-08-31       Impact factor: 49.962

Review 10.  Sonic hedgehog signalling in T-cell development and activation.

Authors:  Tessa Crompton; Susan V Outram; Ariadne L Hager-Theodorides
Journal:  Nat Rev Immunol       Date:  2007-08-10       Impact factor: 53.106
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  20 in total

1.  Inhibition of hedgehog signaling by stereochemically defined des-triazole itraconazole analogues.

Authors:  Jiachen Wen; Kelly A Teske; M Kyle Hadden
Journal:  Bioorg Med Chem Lett       Date:  2019-11-09       Impact factor: 2.823

Review 2.  Hedgehog signaling in the stomach.

Authors:  Daniel Konstantinou; Nina Bertaux-Skeirik; Yana Zavros
Journal:  Curr Opin Pharmacol       Date:  2016-10-14       Impact factor: 5.547

Review 3.  The genetics and molecular biology of T-ALL.

Authors:  Tiziana Girardi; Carmen Vicente; Jan Cools; Kim De Keersmaecker
Journal:  Blood       Date:  2017-01-23       Impact factor: 22.113

4.  Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia.

Authors:  Carmen Vicente; Claire Schwab; Michaël Broux; Ellen Geerdens; Sandrine Degryse; Sofie Demeyer; Idoya Lahortiga; Alannah Elliott; Lucy Chilton; Roberta La Starza; Cristina Mecucci; Peter Vandenberghe; Nicholas Goulden; Ajay Vora; Anthony V Moorman; Jean Soulier; Christine J Harrison; Emmanuelle Clappier; Jan Cools
Journal:  Haematologica       Date:  2015-07-23       Impact factor: 9.941

Review 5.  Medulloblastoma drugs in development: Current leads, trials and drawbacks.

Authors:  Jiachen Wen; M Kyle Hadden
Journal:  Eur J Med Chem       Date:  2021-02-08       Impact factor: 6.514

6.  Activation of hedgehog signaling associates with early disease progression in chronic lymphocytic leukemia.

Authors:  Emanuela M Ghia; Laura Z Rassenti; Donna S Neuberg; Alejandro Blanco; Fouad Yousif; Erin N Smith; John D McPherson; Thomas J Hudson; Olivier Harismendy; Kelly A Frazer; Thomas J Kipps
Journal:  Blood       Date:  2019-03-28       Impact factor: 25.476

7.  Molecular pathway activation features of pediatric acute myeloid leukemia (AML) and acute lymphoblast leukemia (ALL) cells.

Authors:  Ivan Petrov; Maria Suntsova; Olga Mutorova; Maxim Sorokin; Andrew Garazha; Elena Ilnitskaya; Pavel Spirin; Sergey Larin; Olga Kovalchuk; Vladimir Prassolov; Alex Zhavoronkov; Alexander Roumiantsev; Anton Buzdin
Journal:  Aging (Albany NY)       Date:  2016-11-19       Impact factor: 5.682

Review 8.  Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia.

Authors:  Deborah Bongiovanni; Valentina Saccomani; Erich Piovan
Journal:  Int J Mol Sci       Date:  2017-09-05       Impact factor: 5.923

Review 9.  Clinical Assessment and Diagnosis of Germline Predisposition to Hematopoietic Malignancies: The University of Chicago Experience.

Authors:  Ami V Desai; Melody Perpich; Lucy A Godley
Journal:  Front Pediatr       Date:  2017-12-06       Impact factor: 3.418

10.  Sonic Hedgehog regulates thymic epithelial cell differentiation.

Authors:  José Ignacio Saldaña; Anisha Solanki; Ching-In Lau; Hemant Sahni; Susan Ross; Anna L Furmanski; Masahiro Ono; Georg Holländer; Tessa Crompton
Journal:  J Autoimmun       Date:  2016-01-06       Impact factor: 7.094
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