| Literature DB >> 25526530 |
Yea-Lih Lin1, Philippe Pasero2.
Abstract
Unscheduled RNA-DNA hybrids promote the formation DNA double-strand breaks (DSBs) through poorly characterized mechanism. In this issue, Sollier et al. (2014) show that R-loops are processed by XPF and XPG, two structure-specific endonucleases of the NER pathway, to generate DSBs.Entities:
Mesh：
Year: 2014 PMID： 25526530 DOI： 10.1016/j.molcel.2014.12.011
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970