Tobias Hesper1, Falk R Miese2, Harish S Hosalkar3, Michael Behringer4, Christoph Zilkens1, Gerald Antoch2, Rüdiger Krauspe1, Bernd Bittersohl5. 1. University Düsseldorf, Medical Faculty, Department of Orthopaedics, Düsseldorf, Germany. 2. University Düsseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Düsseldorf, Germany. 3. Center of Hip Preservation and Children's Orthopaedics, San Diego, CA, USA. 4. German Sport University, Cologne, Germany. 5. University Düsseldorf, Medical Faculty, Department of Orthopaedics, Düsseldorf, Germany. Electronic address: bbittersohl@partners.org.
Abstract
OBJECTIVE: To study the effect of repetitive joint loading on the T2(*) assessment of knee joint cartilage. MATERIALS AND METHODS: T2(*) mapping was performed in 10 non-professional marathon runners (mean age: 28.7±3.97 years) with no morphologically evident cartilage damage within 48h prior to and following the marathon and after a period of approximately four weeks. Bulk and zonal T2(*) values at the medial and lateral tibiofemoral compartment and the patellofemoral compartment were assessed by means of region of interest analysis. Pre- and post-marathon values were compared. RESULTS: There was a small increase in the T2(*) after running the marathon (30.47±5.16ms versus 29.84±4.97ms, P<0.05) while the T2(*) values before the marathon and those after the period of convalescence were similar (29.84±4.97ms versus 29.81±5.17ms, P=0.855). Regional analyses revealed lower T2(*) values in the medial tibial plateau (P<0.001). CONCLUSIONS: It appears that repetitive joint loading has a transient influence on the T2(*) values. However, this effect is small and probably not clinically relevant. The low T2(*) values in the medial tibial plateau may be related to functional demand or early cartilage degeneration.
OBJECTIVE: To study the effect of repetitive joint loading on the T2(*) assessment of knee joint cartilage. MATERIALS AND METHODS: T2(*) mapping was performed in 10 non-professional marathon runners (mean age: 28.7±3.97 years) with no morphologically evident cartilage damage within 48h prior to and following the marathon and after a period of approximately four weeks. Bulk and zonal T2(*) values at the medial and lateral tibiofemoral compartment and the patellofemoral compartment were assessed by means of region of interest analysis. Pre- and post-marathon values were compared. RESULTS: There was a small increase in the T2(*) after running the marathon (30.47±5.16ms versus 29.84±4.97ms, P<0.05) while the T2(*) values before the marathon and those after the period of convalescence were similar (29.84±4.97ms versus 29.81±5.17ms, P=0.855). Regional analyses revealed lower T2(*) values in the medial tibial plateau (P<0.001). CONCLUSIONS: It appears that repetitive joint loading has a transient influence on the T2(*) values. However, this effect is small and probably not clinically relevant. The low T2(*) values in the medial tibial plateau may be related to functional demand or early cartilage degeneration.
Authors: Michaela C M Khan; James O'Donovan; Jesse M Charlton; Jean-Sébastien Roy; Michael A Hunt; Jean-Francois Esculier Journal: Sports Med Date: 2021-09-03 Impact factor: 11.928
Authors: Leiyu Qiu; Jose Perez; Christopher Emerson; Carlos M Barrera; Jianping Zhong; Fong Nham; Jean Jose; Bryson P Lesniak; Lee D Kaplan; Michael G Baraga Journal: J Int Med Res Date: 2019-09-30 Impact factor: 1.671
Authors: Lauren N Heckelman; Wyatt A R Smith; Alexie D Riofrio; Emily N Vinson; Amber T Collins; Olivia R Gwynn; Gangadhar M Utturkar; Adam P Goode; Charles E Spritzer; Louis E DeFrate Journal: Sci Rep Date: 2020-02-05 Impact factor: 4.379
Authors: Laura Maria Horga; Johann Henckel; Anastasia Fotiadou; Anna C Hirschmann; Anna Di Laura; Camilla Torlasco; Andrew D'Silva; Sanjay Sharma; James C Moon; Alister J Hart Journal: Skeletal Radiol Date: 2020-02-17 Impact factor: 2.199