Literature DB >> 25520526

How Do Small Things Make a Big Difference? Activities to Teach about Human-Microbe Interactions.

Chandana Jasti1, Barbara Hug2, Jillian L Waters3, Rachel J Whitaker4.   

Abstract

Recent scientific studies are providing increasing evidence for how microbes living in and on us are essential to our good health. However, many students still think of microbes only as germs that harm us. The classroom activities presented here are designed to shift student thinking on this topic. In these guided inquiry activities, students investigate human-microbe interactions as they work together to interpret and analyze authentic data from published articles and develop scientific models. Through the activities, students learn and apply ecological concepts as they come to see the human body as a fascinatingly complex ecosystem.

Entities:  

Keywords:  Inquiry instruction; NGSS; curriculum development; data analysis; high school biology; human health; microbiology; models

Year:  2014        PMID： 25520526      PMCID： PMC4266583          DOI： 10.1525/abt.2014.76.9.6

Source DB:  PubMed          Journal:  Am Biol Teach        ISSN： 0002-7685            Impact factor:   0.342


  10 in total

Review 1.  Skin microbiome: genomics-based insights into the diversity and role of skin microbes.

Authors:  Heidi H Kong
Journal:  Trends Mol Med       Date:  2011-03-04       Impact factor: 11.951

2.  Induction of colonic regulatory T cells by indigenous Clostridium species.

Authors:  Koji Atarashi; Takeshi Tanoue; Tatsuichiro Shima; Akemi Imaoka; Tomomi Kuwahara; Yoshika Momose; Genhong Cheng; Sho Yamasaki; Takashi Saito; Yusuke Ohba; Tadatsugu Taniguchi; Kiyoshi Takeda; Shohei Hori; Ivaylo I Ivanov; Yoshinori Umesaki; Kikuji Itoh; Kenya Honda
Journal:  Science       Date:  2010-12-23       Impact factor: 47.728

3.  A humanized gnotobiotic mouse model of host-archaeal-bacterial mutualism.

Authors:  Buck S Samuel; Jeffrey I Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-16       Impact factor: 11.205

Review 4.  The skin microbiome.

Authors:  Elizabeth A Grice; Julia A Segre
Journal:  Nat Rev Microbiol       Date:  2011-04       Impact factor: 60.633

Review 5.  How regulatory T cells work.

Authors:  Dario A A Vignali; Lauren W Collison; Creg J Workman
Journal:  Nat Rev Immunol       Date:  2008-07       Impact factor: 53.106

6.  Methane and hydrogen positivity on breath test is associated with greater body mass index and body fat.

Authors:  R Mathur; M Amichai; K S Chua; J Mirocha; G M Barlow; M Pimentel
Journal:  J Clin Endocrinol Metab       Date:  2013-03-26       Impact factor: 5.958

Review 7.  Mechanisms of microbial traversal of the blood-brain barrier.

Authors:  Kwang Sik Kim
Journal:  Nat Rev Microbiol       Date:  2008-07-07       Impact factor: 60.633

8.  Topographical and temporal diversity of the human skin microbiome.

Authors:  Elizabeth A Grice; Heidi H Kong; Sean Conlan; Clayton B Deming; Joie Davis; Alice C Young; Gerard G Bouffard; Robert W Blakesley; Patrick R Murray; Eric D Green; Maria L Turner; Julia A Segre
Journal:  Science       Date:  2009-05-29       Impact factor: 47.728

9.  Fidaxomicin preserves the intestinal microbiome during and after treatment of Clostridium difficile infection (CDI) and reduces both toxin reexpression and recurrence of CDI.

Authors:  Thomas J Louie; Kris Cannon; Brendan Byrne; Judy Emery; Linda Ward; Melissa Eyben; Walter Krulicki
Journal:  Clin Infect Dis       Date:  2012-08       Impact factor: 9.079

10.  Development of the human infant intestinal microbiota.

Authors:  Chana Palmer; Elisabeth M Bik; Daniel B DiGiulio; David A Relman; Patrick O Brown
Journal:  PLoS Biol       Date:  2007-06-26       Impact factor: 8.029
  10 in total
  1 in total

1.  Early-life influences on obesity: from preconception to adolescence.

Authors:  Mark L Wahlqvist; Stephen A Krawetz; Nico S Rizzo; Maria Gloria Dominguez-Bello; Linda M Szymanski; Shari Barkin; Ann Yatkine; Robert A Waterland; Julie A Mennella; Mina Desai; Michael G Ross; Nancy F Krebs; Bridget E Young; Jane Wardle; Christiane D Wrann; John G Kral
Journal:  Ann N Y Acad Sci       Date:  2015-06-02       Impact factor: 5.691
  1 in total

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