Literature DB >> 25514541

Temperament and behavior in toddlers of mothers with bipolar disorder: a preliminary investigation of a population at high familial risk for psychopathology.

Diana I Simeonova1, Ashraf M Attalla, Theresa Nguyen, Emily Stagnaro, Bettina T Knight, W Edward Craighead, Zachary N Stowe, D Jeffrey Newport.   

Abstract

OBJECTIVE: There are no published studies examining concurrent associations between temperament and behavior during toddlerhood in offspring of parents with bipolar disorder (OBD), a population at high familial risk for psychopathology. Better understanding of early determinants contributing to well-being or mental illness in this high-risk population has the potential to aid in the identification of problem domains to be targeted clinically, and facilitate the development of early intervention and prevention initiatives for an appropriate subgroup of children at the youngest possible age.
METHODS: A total of 30 offspring of mothers with BD (mean age=25.4±4.9 months) participated in this study at Emory University. The mothers completed the Early Childhood Behavior Questionnaire (ECBQ) and the Child Behavior Checklist (CBCL).
RESULTS: The results of the correlational analyses indicated that the broad temperament dimension Negative Affectivity and the individual ECBQ scales Sadness and Shyness were positively associated with the broad CBCL dimension Internalizing Problems, whereas Sociability was negatively associated with Internalizing Problems. In addition, the temperament scales Soothability and Frustration were negatively and positively associated with Internalizing Problems, respectively. All ECBQ scales included in the broad temperament dimension Effortful Control, except for Cuddliness, were significantly negatively associated with the broad CBCL dimension Externalizing Problems. A significant sex difference was found for the ECBQ scale Positive Anticipation and the CBCL scale Sleep Problems, with a higher mean rank score for girls than for boys.
CONCLUSIONS: This is the first systematic investigation of temperament and behavior and concurrent associations between these two domains in toddlers of mothers with BD. The present findings provide a platform for future investigations of the contribution of temperament and early behavior to potential well-being or mental illness in OBD.

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Year:  2014        PMID: 25514541      PMCID: PMC4268554          DOI: 10.1089/cap.2013.0136

Source DB:  PubMed          Journal:  J Child Adolesc Psychopharmacol        ISSN: 1044-5463            Impact factor:   2.576


  27 in total

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Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2000-05       Impact factor: 8.829

4.  Revealing the relation between temperament and behavior problem symptoms by eliminating measurement confounding: expert ratings and factor analyses.

Authors:  Kathryn S Lemery; Marilyn J Essex; Nancy A Smider
Journal:  Child Dev       Date:  2002 May-Jun

Review 5.  Linking temperamental fearfulness and anxiety symptoms: a behavior-genetic perspective.

Authors:  H H Goldsmith; K S Lemery
Journal:  Biol Psychiatry       Date:  2000-12-15       Impact factor: 13.382

6.  The CBCL predicts DSM bipolar disorder in children: a receiver operating characteristic curve analysis.

Authors:  Stephen V Faraone; Robert R Althoff; James J Hudziak; Michael Monuteaux; Joseph Biederman
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7.  Childhood anxiety: an early predictor of mood disorders in offspring of bipolar parents.

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8.  Early childhood temperament in pediatric bipolar disorder and attention deficit hyperactivity disorder.

Authors:  Amy E West; Lindsay S Schenkel; Mani N Pavuluri
Journal:  J Clin Psychol       Date:  2008-04

9.  Subcortical volumetric correlates of anxiety in familial pediatric bipolar disorder: a preliminary investigation.

Authors:  Diana I Simeonova; Valerie Jackson; Ashraf Attalla; Asya Karchemskiy; Meghan Howe; Nancy Adleman; Kiki Chang
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10.  Mental health and functional outcomes of maternal and adolescent reports of adolescent depressive symptoms.

Authors:  Frances Rice; Kate J Lifford; Hollie V Thomas; Anita Thapar
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2007-09       Impact factor: 8.829

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Journal:  Eur Child Adolesc Psychiatry       Date:  2018-03-08       Impact factor: 4.785

Review 2.  Course of Illness and Treatment Updates for Bipolar Disorder in the Perinatal Period.

Authors:  Melissa M Batt; Aviva K Olsavsky; Shaleah Dardar; Celeste St John-Larkin; Rachel L Johnson; Mary D Sammel
Journal:  Curr Psychiatry Rep       Date:  2022-02-15       Impact factor: 8.081

3.  Offspring of mothers with bipolar disorder: a systematic review considering personality features.

Authors:  Rodrigo A Bastos; Lia S Campos; Débora B Faria-Schützer; Maíra E Brito; Diego R da Silva; Amilton Dos Santos-Junior; Egberto R Turato
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