Literature DB >> 25512789

Cardiac adipose tissue and its relationship to diabetes mellitus and cardiovascular disease.

Adam M Noyes1, Kirandeep Dua1, Ramprakash Devadoss1, Lovely Chhabra1.   

Abstract

Type-2 diabetes mellitus (T2DM) plays a central role in the development of cardiovascular disease (CVD). However, its relationship to epicardial adipose tissue (EAT) and pericardial adipose tissue (PAT) in particular is important in the pathophysiology of coronary artery disease. Owing to its close proximity to the heart and coronary vasculature, EAT exerts a direct metabolic impact by secreting proinflammatory adipokines and free fatty acids, which promote CVD locally. In this review, we have discussed the relationship between T2DM and cardiac fat deposits, particularly EAT and PAT, which together exert a big impact on the cardiovascular health.

Entities:  

Keywords:  Cardiovascular disease; Epicardial adipose tissue; Pericardial adipose tissue; Type 2 diabetes

Year:  2014        PMID： 25512789      PMCID： PMC4265873          DOI： 10.4239/wjd.v5.i6.868

Source DB:  PubMed          Journal:  World J Diabetes        ISSN： 1948-9358


  85 in total

1.  Pericardial adipose tissue, atherosclerosis, and cardiovascular disease risk factors: the Jackson Heart Study: comment on Liu et Al.

Authors:  Gianluca Iacobellis; Alexis Elias Malavazos
Journal:  Diabetes Care       Date:  2010-09       Impact factor: 19.112

2.  Epicardial and pericardial fat: close, but very different.

Authors:  Gianluca Iacobellis
Journal:  Obesity (Silver Spring)       Date:  2009-04       Impact factor: 5.002

Review 3.  Echocardiographic epicardial fat: a review of research and clinical applications.

Authors:  Gianluca Iacobellis; Howard J Willens
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5.  Relationship between epicardial fat measured by 64-multidetector computed tomography and coronary artery disease.

Authors:  Kohichiro Iwasaki; Takeshi Matsumoto; Hitoshi Aono; Hiroshi Furukawa; Masanobu Samukawa
Journal:  Clin Cardiol       Date:  2011-02-01       Impact factor: 2.882

6.  Association between carotid intima-media thickness and pericardial fat in the Multi-Ethnic Study of Atherosclerosis (MESA).

Authors:  Elsayed Z Soliman; Jingzhong Ding; Fang-Chi Hsu; J Jeffrey Carr; Joseph F Polak; David C Goff
Journal:  J Stroke Cerebrovasc Dis       Date:  2010-01       Impact factor: 2.136

7.  Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease.

Authors:  Gianluca Iacobellis; Daniela Pistilli; Marco Gucciardo; Frida Leonetti; Fabio Miraldi; Gianluca Brancaccio; Pietro Gallo; Cira Rosaria Tiziana di Gioia
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8.  Pioglitazone improves cardiac function and alters myocardial substrate metabolism without affecting cardiac triglyceride accumulation and high-energy phosphate metabolism in patients with well-controlled type 2 diabetes mellitus.

Authors:  Rutger W van der Meer; Luuk J Rijzewijk; Hugo W A M de Jong; Hildo J Lamb; Mark Lubberink; Johannes A Romijn; Jeroen J Bax; Albert de Roos; Otto Kamp; Walter J Paulus; Robert J Heine; Adriaan A Lammertsma; Johannes W A Smit; Michaela Diamant
Journal:  Circulation       Date:  2009-04-06       Impact factor: 29.690

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Authors:  Gianluca Iacobellis; Arya M Sharma; Adriano M Pellicelli; Benvenuto Grisorio; Giorgio Barbarini; Giuseppe Barbaro
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Review 10.  Interatrial block in the modern era.

Authors:  Lovely Chhabra; Ramprakash Devadoss; Vinod K Chaubey; David H Spodick
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  16 in total

1.  Epicardial adipose tissue is associated with high-risk plaque feature progression in non-culprit lesions.

Authors:  Yahang Tan; Jia Zhou; Ying Zhou; Xiaobo Yang; Jing Wang; Yundai Chen
Journal:  Int J Cardiovasc Imaging       Date:  2017-05-26       Impact factor: 2.357

2.  Increased Epicardial Fat Volume Is Independently Associated with the Presence and Severity of Systemic Sclerosis.

Authors:  Benjamin D Long; Jadranka Stojanovska; Richard K J Brown; Anil K Attili; Eizabeth A Jackson; Vladimir Ognenovski
Journal:  Acad Radiol       Date:  2017-08-26       Impact factor: 3.173

Review 3.  Relevance of mitochondrial dysfunction in heart disease associated with insulin resistance conditions.

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4.  Meta-Analysis of Non-Alcoholic Fatty Liver Disease and Electromechanical Reconstruction of Myocardium.

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Journal:  Arch Razi Inst       Date:  2022-02-28

Review 5.  Epicardial Adipose Tissue as an Independent Cardiometabolic Risk Factor for Coronary Artery Disease.

Authors:  Nikoleta Karampetsou; Leonidas Alexopoulos; Aggeliki Minia; Vaia Pliaka; Nikos Tsolakos; Konstantinos Kontzoglou; Despoina N Perrea; Paulos Patapis
Journal:  Cureus       Date:  2022-06-01

6.  Epicardial adipose tissue in long-term hemodialysis patients: its association with vascular calcification and long-term development.

Authors:  Xoana Barros; Timm Dirrichs; Ralf Koos; Sebastian Reinartz; Nadine Kaesler; Rafael Kramann; Ulrich Gladziwa; Markus Ketteler; Jürgen Floege; Nikolaus Marx; José V Torregrosa; András Keszei; Vincent M Brandenburg
Journal:  J Nephrol       Date:  2015-08-08       Impact factor: 3.902

7.  Hepatic and Skeletal Muscle Adiposity Are Associated with Diabetes Independent of Visceral Adiposity in Nonobese African-Caribbean Men.

Authors:  Iva Miljkovic; Allison L Kuipers; Ryan K Cvejkus; J Jeffrey Carr; James G Terry; Bharat Thyagarajan; Victor W Wheeler; Sangeeta Nair; Joseph M Zmuda
Journal:  Metab Syndr Relat Disord       Date:  2020-05-11       Impact factor: 1.894

8.  Role of miRNAs in Epicardial Adipose Tissue in CAD Patients with T2DM.

Authors:  Yang Liu; Wenbo Fu; Mu Lu; Shitao Huai; Yaqin Song; Yutao Wei
Journal:  Biomed Res Int       Date:  2016-08-14       Impact factor: 3.411

9.  Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model.

Authors:  María E Cabalén; María F Cabral; Liliana M Sanmarco; Marta C Andrada; Luisina I Onofrio; Nicolás E Ponce; María P Aoki; Susana Gea; Roxana C Cano
Journal:  Oncotarget       Date:  2016-03-22

10.  Associations of C1q/TNF-Related Protein-9 Levels in Serum and Epicardial Adipose Tissue with Coronary Atherosclerosis in Humans.

Authors:  Jing Wang; Tao Hang; Xun-Min Cheng; De-Min Li; Qi-Gao Zhang; Li-Jun Wang; Yong-Ping Peng; Jian-Bin Gong
Journal:  Biomed Res Int       Date:  2015-09-17       Impact factor: 3.411
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