Literature DB >> 2550883

Effects of calmidazolium and dibutyryl cyclic AMP on the longitudinal internal resistance in sinus node strips.

W Tuganowski1, I Korczyńska, K Wasik, G Piatek.   

Abstract

The effects of calmidazolium (10(-7) mol/l) and db cAMP (10(-3) mol/l) on the longitudinal internal resistance (ri) in the rabbit sinus node strips were studied by means of microelectrode and extracellular recording techniques. Calmidazolium (CDZ) decreased ri by 27%. An addition of db cAMP to the CDZ-containing Tyrode potentiated this effect by further 14%. db cAMP initially decreased ri by 17%, then it enhanced this resistance by 7% above the pretreatment control value. An addition of CDZ to the db cAMP-containing Tyrode reduced ri by 41% below the pretreatment control. Possible mechanisms underlying these effects were discussed in terms of cAMP, Cai, and calmodulin action on the cell coupling.

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Year:  1989        PMID： 2550883     DOI： 10.1007/BF00584638

Source DB:  PubMed          Journal:  Pflugers Arch        ISSN： 0031-6768            Impact factor:   3.657


  12 in total

1.  Derivatives of cyclic 3',5'-adenosine monophosphate.

Authors:  T POSTERNAK; E W SUTHERLAND; W F HENION
Journal:  Biochim Biophys Acta       Date:  1962-12-17

Review 2.  Effects of pCai and pHi on cell-to-cell coupling.

Authors:  M L Pressler
Journal:  Experientia       Date:  1987-10-15

3.  A method of measurement of longitudinal resistances in an isolated cardiac and smooth muscle preparation.

Authors:  W Tuganowski; M Bukowski; I Korczyńska; B Wójcik; K Wasik
Journal:  Pflugers Arch       Date:  1986-02       Impact factor: 3.657

4.  Effect of intracellular injection of cAMP on the electrical coupling of mammalian cardiac cells.

Authors:  W C De Mello
Journal:  Biochem Biophys Res Commun       Date:  1984-03-30       Impact factor: 3.575

5.  Calmodulin-like proteins and communicating junctions. Electrical uncoupling of crayfish septate axons is inhibited by the calmodulin inhibitor W7 and is not affected by cyclic nucleotides.

Authors:  C Peracchia
Journal:  Pflugers Arch       Date:  1987-04       Impact factor: 3.657

6.  cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide.

Authors:  J C Saez; D C Spray; A C Nairn; E Hertzberg; P Greengard; M V Bennett
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

7.  Effect of intracellular injection of calcium and strontium on cell communication in heart.

Authors:  W C De Mello
Journal:  J Physiol       Date:  1975-09       Impact factor: 5.182

8.  Inotropic agents modulate gap junctional conductance between cardiac myocytes.

Authors:  J M Burt; D C Spray
Journal:  Am J Physiol       Date:  1988-06

9.  Is calmodulin involved in the regulation of gap junction permeability?

Authors:  C Peracchia; G Bernardini; L L Peracchia
Journal:  Pflugers Arch       Date:  1983-10       Impact factor: 3.657

10.  Communicating junctions and calmodulin: inhibition of electrical uncoupling in Xenopus embryo by calmidazolium.

Authors:  C Peracchia
Journal:  J Membr Biol       Date:  1984       Impact factor: 1.843
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  5 in total

1.  Phosphorylation of connexin in functional regulation of the cardiac gap junction.

Authors:  Issei Imanaga; Lin Hai; Koichi Ogawa; Ken Matsumura; Takashi Mayama
Journal:  Exp Clin Cardiol       Date:  2004

2.  Effects of cyclic AMP on the function of the cardiac gap junction during hypoxia.

Authors:  Ken Matsumura; Takashi Mayama; Hai Lin; Yasuji Sakamoto; Koichi Ogawa; Issei Imanaga
Journal:  Exp Clin Cardiol       Date:  2006

Review 3.  Calmodulin-Cork Model of Gap Junction Channel Gating-One Molecule, Two Mechanisms.

Authors:  Camillo Peracchia
Journal:  Int J Mol Sci       Date:  2020-07-13       Impact factor: 5.923

Review 4.  Calmodulin-Connexin Partnership in Gap Junction Channel Regulation-Calmodulin-Cork Gating Model.

Authors:  Camillo Peracchia; Lillian Mae Leverone Peracchia
Journal:  Int J Mol Sci       Date:  2021-12-02       Impact factor: 5.923

Review 5.  Calmodulin-Mediated Regulation of Gap Junction Channels.

Authors:  Camillo Peracchia
Journal:  Int J Mol Sci       Date:  2020-01-12       Impact factor: 5.923
  5 in total

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