Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Effect of intracellular injection of calcium and strontium on cell communication in heart.

Literature DB >> 1177142

Effect of intracellular injection of calcium and strontium on cell communication in heart.

Abstract

1. The influence of Ca and Sr on the electrical coupling of canine Purkinje cells was investigated by injecting the ions electrophoretically into the cytoplasm. 2. It was found that the intracellular injection produced electrical uncoupling which was spontaneously reversed. 3. No change in resting potential of the cell adjacent to the injection site was found except in those fibres not completely healed. 4. The input resistance of the injected cell increased concomitantly with the establishment of the electrical uncoupling. 5. Caffeine (6mM), added to the extracellular fluid, reduced the rate of spontaneous recoupling. Reduction of temperature of the Tyrode solution had the same effect. 6. The abolition of cell communication produced by Ca injection seems to indicate that the ion plays an important role in the control of junctional conductance in heart fibres.

Entities: Chemical Species

Mesh：

Substances：

Year: 1975 PMID： 1177142 PMCID： PMC1348358 DOI： 10.1113/jphysiol.1975.sp011051

Source DB: PubMed Journal: J Physiol ISSN： 0022-3751 Impact factor: 5.182

15 in total

1. COMPARISON OF THE ULTRASTRUCTURAL BASIS OF THE CONTRACTILE PROCESS IN HEART AND SKELETAL MUSCLE.

Authors: D SPIRO; E H SONNENBLICK
Journal: Circ Res Date: 1964-11 Impact factor: 17.367

2. On the localization of acetylcholine receptors.

Authors: J DEL CASTILLO; B KATZ
Journal: J Physiol Date: 1955-04-28 Impact factor: 5.182

3. Accumulation of calcium (or strontium) under conditions of increasing contractility.

Authors: R NIEDERGERKE; E J HARRIS
Journal: Nature Date: 1957-05-25 Impact factor: 49.962

4. Temperature effects on the electrical activity of Purkinje fibres.

Authors: E CORABOEUF; S WEIDMANN
Journal: Helv Physiol Pharmacol Acta Date: 1954

5. The electrical constants of Purkinje fibres.

Authors: S WEIDMANN
Journal: J Physiol Date: 1952-11 Impact factor: 5.182

6. An analysis of the end-plate potential recorded with an intracellular electrode.

Authors: P FATT; B KATZ
Journal: J Physiol Date: 1951-11-28 Impact factor: 5.182

7. Influence of temperature on myocardial healing-over.

Authors: W C De Mello
Journal: Experientia Date: 1972-07-15

8. A study on the healing-over of myocardial cells of toads.

Authors: W C de Mello; G E Motta; M Chapeau
Journal: Circ Res Date: 1969-03 Impact factor: 17.367

9. The diffusion of radiopotassium across intercalated disks of mammalian cardiac muscle.

Authors: S Weidmann
Journal: J Physiol Date: 1966-11 Impact factor: 5.182

10. Junctional membrane uncoupling. Permeability transformations at a cell membrane junction.

Authors: W R Loewenstein; M Nakas; S J Socolar
Journal: J Gen Physiol Date: 1967-08 Impact factor: 4.086

83 in total

1. Conformational changes in surface structures of isolated connexin 26 gap junctions.

Authors: Daniel J Müller; Galen M Hand; Andreas Engel; Gina E Sosinsky
Journal: EMBO J Date: 2002-07-15 Impact factor: 11.598

2. Gating of connexin 43 gap junctions by a cytoplasmic loop calmodulin binding domain.

Authors: Qin Xu; Richard F Kopp; Yanyi Chen; Jenny J Yang; Michael W Roe; Richard D Veenstra
Journal: Am J Physiol Cell Physiol Date: 2012-03-14 Impact factor: 4.249

3. Influence of the sodium pump on intercellular communication in heart fibres: effect of intracellular injection of sodium ion on electrical coupling.

Authors: W C De Mello
Journal: J Physiol Date: 1976-12 Impact factor: 5.182

Effect of intracellular injection of calcium and strontium on cell communication in heart.

1. COMPARISON OF THE ULTRASTRUCTURAL BASIS OF THE CONTRACTILE PROCESS IN HEART AND SKELETAL MUSCLE.

2. On the localization of acetylcholine receptors.

3. Accumulation of calcium (or strontium) under conditions of increasing contractility.

4. Temperature effects on the electrical activity of Purkinje fibres.

5. The electrical constants of Purkinje fibres.

6. An analysis of the end-plate potential recorded with an intracellular electrode.

7. Influence of temperature on myocardial healing-over.

8. A study on the healing-over of myocardial cells of toads.

9. The diffusion of radiopotassium across intercalated disks of mammalian cardiac muscle.

10. Junctional membrane uncoupling. Permeability transformations at a cell membrane junction.

1. Conformational changes in surface structures of isolated connexin 26 gap junctions.

2. Gating of connexin 43 gap junctions by a cytoplasmic loop calmodulin binding domain.

3. Influence of the sodium pump on intercellular communication in heart fibres: effect of intracellular injection of sodium ion on electrical coupling.

4. Anisotropic conduction block and reentry in neonatal rat ventricular myocyte monolayers.

5. Influence of electrophysiological heterogeneity on electrical stimulation in healthy and failing human hearts.

Review 6. Influence of anisotropic conduction properties in the propagation of the cardiac action potential.

7. Effects of calmidazolium and dibutyryl cyclic AMP on the longitudinal internal resistance in sinus node strips.

8. Gap junction gating sensitivity to physiological internal calcium regardless of pH in Novikoff hepatoma cells.

9. Drugs that block calmoduLin activity inhibit cell-to-cell coupling in the epidermis of Tenebrio molitor.

10. RXP-E: a connexin43-binding peptide that prevents action potential propagation block.