Literature DB >> 25506052

The Virtual Patient Simulator of Deep Brain Stimulation in the Obsessive Compulsive Disorder Based on Connectome and 7 Tesla MRI Data.

Giorgio Bonmassar1, Nikos Makris1.   

Abstract

We present work in progress on the virtual patient model for patients with Deep Brain Stimulation (DBS) implants based on Connectome and 7 Tesla Magnetic Resonance Imaging (MRI) data. Virtual patients are realistic computerized models of patients that allow medical-device companies to test new products earlier, helping the devices get to market more quickly and cheaply according to the Food and Drug Administration. We envision that the proposed new virtual patient simulator will enable radio frequency power dosimetry on patients with the DBS implant undergoing MRI. Future patients with DBS implants may profit from the proposed virtual patient by allowing for a MRI investigation instead of more invasive Computed Tomography (CT) scans. The virtual patient will be flexible and morphable to relate to neurological and psychiatric conditions such as Obsessive Compulsive Disorder (OCD), which benefit from DBS.

Entities:  

Keywords:  7 Tesla MRI; CT; DBS; MRI; MRI safety; OCD; SAR; VPS; connectome; deep brain brain stimulation; obsessive compulsive disorder; specific absorption rate; virtual patient simulator

Year:  2014        PMID: 25506052      PMCID: PMC4260261     

Source DB:  PubMed          Journal:  Cogn Int Conf Adv Cogn Technol Appl        ISSN: 2308-4197


  17 in total

1.  Patient-specific analysis of the volume of tissue activated during deep brain stimulation.

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Journal:  Med Biol Eng Comput       Date:  2008-11-05       Impact factor: 2.602

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Journal:  Cereb Cortex       Date:  1994 Jul-Aug       Impact factor: 5.357

9.  Permanent neurological deficit related to magnetic resonance imaging in a patient with implanted deep brain stimulation electrodes for Parkinson's disease: case report.

Authors:  Jaimie M Henderson; Jean Tkach; Michael Phillips; Kenneth Baker; Frank G Shellock; Ali R Rezai
Journal:  Neurosurgery       Date:  2005-11       Impact factor: 4.654

10.  Specific absorption rate studies of the parallel transmission of inner-volume excitations at 7T.

Authors:  Adam C Zelinski; Leonardo M Angelone; Vivek K Goyal; Giorgio Bonmassar; Elfar Adalsteinsson; Lawrence L Wald
Journal:  J Magn Reson Imaging       Date:  2008-10       Impact factor: 4.813

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  1 in total

1.  A Virtual Patient Simulator Based on Human Connectome and 7 T MRI for Deep Brain Stimulation.

Authors:  Giorgio Bonmassar; Leonardo M Angelone; Nikos Makris
Journal:  Int J Adv Life Sci       Date:  2014
  1 in total

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