Literature DB >> 25495406

Polymorphic expression of CYP2C19 and CYP2D6 in the developing and adult human brain causing variability in cognition, risk for depression and suicide: the search for the endogenous substrates.

Magnus Ingelman-Sundberg1, Anna Persson, Marin M Jukic.   

Abstract

Entities:  

Keywords:  GABA receptors; depression; endocannabinoids; gene duplication; serotonin; ultrarapid metabolizer

Mesh：

Substances：

Year:  2014        PMID： 25495406     DOI： 10.2217/pgs.14.151

Source DB:  PubMed          Journal:  Pharmacogenomics        ISSN： 1462-2416            Impact factor:   2.533


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  11 in total

Review 1.  Single Nucleotide Polymorphisms and the Central Nervous System: Potential Biomarkers in Identifying Suicide Risk.

Authors:  Atmaram Yarlagadda; Kevin P Rosenblatt; Anita H Clayton
Journal:  Innov Clin Neurosci       Date:  2017-06-01

Review 2.  Developmental neurotoxicity of succeeding generations of insecticides.

Authors:  Yael Abreu-Villaça; Edward D Levin
Journal:  Environ Int       Date:  2016-11-28       Impact factor: 9.621

3.  Association of the Val66Met polymorphism of the BDNF gene and the deletional mutation of CYP2D6 gene with the prevalence and severity of depressive disorder in an Eastern Indian population.

Authors:  Somnath Haldar; Suparna Roy; Santanu Sen; Anindya Dasgupta; Srijit Ghosh
Journal:  Indian J Psychiatry       Date:  2022-06-08       Impact factor: 2.983

4.  Genome-wide association analyses of symptom severity among clozapine-treated patients with schizophrenia spectrum disorders.

Authors:  C Okhuijsen-Pfeifer; M Z van der Horst; C A Bousman; B Lin; K R van Eijk; S Ripke; Y Ayhan; M O Babaoglu; M Bak; W Alink; H van Beek; E Beld; A Bouhuis; M Edlinger; I M Erdogan; A Ertuğrul; G Yoca; I P Everall; T Görlitz; K P Grootens; S Gutwinski; T Hallikainen; E Jeger-Land; M de Koning; M Lähteenvuo; S E Legge; S Leucht; C Morgenroth; A Müderrisoğlu; A Narang; C Pantelis; A F Pardiñas; T Oviedo-Salcedo; J Schneider-Thoma; S Schreiter; E Repo-Tiihonen; H Tuppurainen; M Veereschild; S Veerman; M de Vos; E Wagner; D Cohen; J P A M Bogers; J T R Walters; A E Anil Yağcıoğlu; J Tiihonen; A Hasan; J J Luykx
Journal:  Transl Psychiatry       Date:  2022-04-07       Impact factor: 7.989

5.  Monoamine Oxidase-A Occupancy by Moclobemide and Phenelzine: Implications for the Development of Monoamine Oxidase Inhibitors.

Authors:  Lina Chiuccariello; Robert G Cooke; Laura Miler; Robert D Levitan; Glen B Baker; Stephen J Kish; Nathan J Kolla; Pablo M Rusjan; Sylvain Houle; Alan A Wilson; Jeffrey H Meyer
Journal:  Int J Neuropsychopharmacol       Date:  2015-08-27       Impact factor: 5.176

Review 6.  Alterations of Cytochrome P450s and UDP-Glucuronosyltransferases in Brain Under Diseases and Their Clinical Significances.

Authors:  Yun Sheng; Hanyu Yang; Tong Wu; Liang Zhu; Li Liu; Xiaodong Liu
Journal:  Front Pharmacol       Date:  2021-04-21       Impact factor: 5.810

7.  Gene prediction of aging-related diseases based on DNN and Mashup.

Authors:  Junhua Ye; Shunfang Wang; Xin Yang; Xianjun Tang
Journal:  BMC Bioinformatics       Date:  2021-12-17       Impact factor: 3.169

8.  Pharmacoresistant Severe Mental Health Disorders in Children and Adolescents: Functional Abnormalities of Cytochrome P450 2D6.

Authors:  Susanne Thümmler; Emmanuelle Dor; Renaud David; Graziella Leali; Michele Battista; Alexia David; Florence Askenazy; Céline Verstuyft
Journal:  Front Psychiatry       Date:  2018-01-24       Impact factor: 4.157

Review 9.  Pharmacogenomics of Antidepressant and Antipsychotic Treatment: How Far Have We Got and Where Are We Going?

Authors:  Roos van Westrhenen; Katherine J Aitchison; Magnus Ingelman-Sundberg; Marin M Jukić
Journal:  Front Psychiatry       Date:  2020-03-12       Impact factor: 4.157

10.  Effects of genetic variability of CYP2D6 on neural substrates of sustained attention during on-task activity.

Authors:  Roberto Viviani; Irene Messina; Julia E Bosch; Lisa Dommes; Anna Paul; Katharina L Schneider; Catharina Scholl; Julia C Stingl
Journal:  Transl Psychiatry       Date:  2020-10-06       Impact factor: 6.222
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