Literature DB >> 25494109

Oral submucous fibrosis in India: Are we progressing??

P B Hebbar1, R Sheshaprasad, S Gurudath, A Pai, D Sujatha.   

Abstract

Oral submucous fibrosis (OSMF) a condition first described in the 1950s in the modern literature still remains elusive of a cure. For many years this condition had been confined to countries like India, Pakistan, Bangladesh, etc., but now this condition is being reported from Western countries as well. Inspite of intensive research over the years into the etiologic factors of OSMF, a single etiologic factor cannot be pointed out with certainty rather several causative factors have been proposed. Patients suffering with OSMF initially present with a blanched or marble-like pale mucosa, vesiculations, and also intolerance to hot and spicy food. Gradually, the patient may develop fibrous bands in the buccal and labial mucosa which causes a restriction in opening the mouth. The evidence for the various treatment modalities for OSMF is weak hence better documentation of the studies performed with standardized criteria is required. The current review aims to refresh our knowledge regarding OSMF from an Indian perspective and make a few suggestions to fill the lacunae in this field.

Entities:  

Year:  2014        PMID: 25494109     DOI: 10.4103/0019-509X.146724

Source DB:  PubMed          Journal:  Indian J Cancer        ISSN: 0019-509X            Impact factor:   1.224


  6 in total

1.  Assessment of Eustachian tube functioning following surgical intervention of Oral Submucus Fibrosis by using tympanometry & audiometry.

Authors:  Sreea Roy; Abhay Taranath Kamath; Manish Bhagania; Adarsh Kudva; Kishan Madikeri Mohan
Journal:  J Oral Biol Craniofac Res       Date:  2019-11-27

2.  Nodal involvement in Oral Squamous Cell Carcinoma (SCC) patients with and without Oral Sub Mucous Fibrosis (OSMF): A Comparative Study.

Authors:  Gaurav Singh; Amar Singh Rana; Anshuman Kumar; Ashish Prajapati; Shubham Kumar; Parul Singh
Journal:  J Oral Biol Craniofac Res       Date:  2017-04-20

Review 3.  Oral submucous fibrosis: a contemporary narrative review with a proposed inter-professional approach for an early diagnosis and clinical management.

Authors:  Naman R Rao; Alessandro Villa; Chandramani B More; Ruwan D Jayasinghe; Alexander Ross Kerr; Newell W Johnson
Journal:  J Otolaryngol Head Neck Surg       Date:  2020-01-08

4.  Small Molecule "Silmitasertib" Repurposed as Inhibitor of Transforming Growth Factor Beta 1 for the Development of Therapeutics for Oral Submucous Fibrosis.

Authors:  Nezar Boreak
Journal:  Biomed Res Int       Date:  2021-04-01       Impact factor: 3.411

5.  Anti-fibrotic activity of licorice extract in comparison with colchicine on areca nut-induced fibroblasts: An in vitro study.

Authors:  Amritha James; Nandhini Gunasekaran; Rajkumar Krishnan; Preethi Arunachalam; Ramya Mahalingam
Journal:  J Oral Maxillofac Pathol       Date:  2022-06-28

6.  EMODIN DOWNREGULATES CELL PROLIFERATION MARKERS DURING DMBA INDUCED ORAL CARCINOGENESIS IN GOLDEN SYRIAN HAMSTERS.

Authors:  Asokan Manimaran; Rajamanickam Buddhan; Shanmugam Manoharan
Journal:  Afr J Tradit Complement Altern Med       Date:  2017-01-13
  6 in total

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