Literature DB >> 25488302

The Salmonella type III secretion system virulence effector forms a new hexameric chaperone assembly for export of effector/chaperone complexes.

Chi-Lin Tsai1, Brianne J Burkinshaw2, Natalie C J Strynadka3, John A Tainer4.   

Abstract

Bacteria hijack eukaryotic cells by injecting virulence effectors into host cytosol with a type III secretion system (T3SS). Effectors are targeted with their cognate chaperones to hexameric T3SS ATPase at the bacterial membrane's cytosolic face. In this issue of the Journal of Bacteriology, Roblin et al. (P. Roblin, F. Dewitte, V. Villeret, E. G. Biondi, and C. Bompard, J Bacteriol 197:688-698, 2015, http://dx.doi.org/10.1128/JB.02294-14) show that the T3SS chaperone SigE of Salmonella can form hexameric rings rather than dimers when bound to its cognate effector, SopB, implying a novel multimeric association for chaperone/effector complexes with their ATPase.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2014        PMID： 25488302      PMCID： PMC4334186          DOI： 10.1128/JB.02524-14

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  33 in total

1.  The structural organization of the N-terminus domain of SopB, a virulence factor of Salmonella, depends on the nature of its protein partners.

Authors:  Pierre Roblin; Pierre Lebrun; Prakash Rucktooa; Frederique Dewitte; Zoe Lens; Véronique Receveur-Brechot; Vincent Raussens; Vincent Villeret; Coralie Bompard
Journal:  Biochim Biophys Acta       Date:  2013-09-26

2.  A Salmonella type three secretion effector/chaperone complex adopts a hexameric ring-like structure.

Authors:  Pierre Roblin; Frédérique Dewitte; Vincent Villeret; Emanuele G Biondi; Coralie Bompard
Journal:  J Bacteriol       Date:  2014-11-17       Impact factor: 3.490

3.  EscO, a functional and structural analog of the flagellar FliJ protein, is a positive regulator of EscN ATPase activity of the enteropathogenic Escherichia coli injectisome.

Authors:  Mariana Romo-Castillo; Angel Andrade; Norma Espinosa; Julia Monjarás Feria; Eduardo Soto; Miguel Díaz-Guerrero; Bertha González-Pedrajo
Journal:  J Bacteriol       Date:  2014-04-04       Impact factor: 3.490

4.  Insights into FlaI functions in archaeal motor assembly and motility from structures, conformations, and genetics.

Authors:  Sophia Reindl; Abhrajyoti Ghosh; Gareth J Williams; Kerstin Lassak; Tomasz Neiner; Anna-Lena Henche; Sonja-Verena Albers; John A Tainer
Journal:  Mol Cell       Date:  2013-02-14       Impact factor: 17.970

5.  Comprehensive macromolecular conformations mapped by quantitative SAXS analyses.

Authors:  Greg L Hura; Helen Budworth; Kevin N Dyer; Robert P Rambo; Michal Hammel; Cynthia T McMurray; John A Tainer
Journal:  Nat Methods       Date:  2013-06       Impact factor: 28.547

6.  Identification of the docking site between a type III secretion system ATPase and a chaperone for effector cargo.

Authors:  Sarah E Allison; Brian R Tuinema; Ellen S Everson; Seiji Sugiman-Marangos; Kun Zhang; Murray S Junop; Brian K Coombes
Journal:  J Biol Chem       Date:  2014-07-17       Impact factor: 5.157

7.  Dynamics of the type III secretion system activity of enteropathogenic Escherichia coli.

Authors:  Erez Mills; Kobi Baruch; Gili Aviv; Mor Nitzan; Ilan Rosenshine
Journal:  MBio       Date:  2013-07-30       Impact factor: 7.867

8.  Architecture of the major component of the type III secretion system export apparatus.

Authors:  Patrizia Abrusci; Marta Vergara-Irigaray; Steven Johnson; Morgan D Beeby; David R Hendrixson; Pietro Roversi; Miriam E Friede; Janet E Deane; Grant J Jensen; Christoph M Tang; Susan M Lea
Journal:  Nat Struct Mol Biol       Date:  2012-12-09       Impact factor: 15.369

9.  Accurate assessment of mass, models and resolution by small-angle scattering.

Authors:  Robert P Rambo; John A Tainer
Journal:  Nature       Date:  2013-04-25       Impact factor: 49.962

10.  Common and distinct structural features of Salmonella injectisome and flagellar basal body.

Authors:  Akihiro Kawamoto; Yusuke V Morimoto; Tomoko Miyata; Tohru Minamino; Kelly T Hughes; Takayuki Kato; Keiichi Namba
Journal:  Sci Rep       Date:  2013-11-28       Impact factor: 4.379
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  5 in total

Review 1.  The Structure and Function of Type III Secretion Systems.

Authors:  Ryan Q Notti; C Erec Stebbins
Journal:  Microbiol Spectr       Date:  2016-02

Review 2.  Methods to Illuminate the Role of Salmonella Effector Proteins during Infection: A Review.

Authors:  Alexandra M Young; Amy E Palmer
Journal:  Front Cell Infect Microbiol       Date:  2017-08-10       Impact factor: 5.293

Review 3.  Delivery of Heterologous Proteins, Enzymes, and Antigens via the Bacterial Type III Secretion System.

Authors:  Heather A Pendergrass; Aaron E May
Journal:  Microorganisms       Date:  2020-05-21

Review 4.  Delivering the pain: an overview of the type III secretion system with special consideration for aquatic pathogens.

Authors:  Hadis Rahmatelahi; Mansour El-Matbouli; Simon Menanteau-Ledouble
Journal:  Vet Res       Date:  2021-12-19       Impact factor: 3.683

5.  Regulation of Effector Delivery by Type III Secretion Chaperone Proteins in Erwinia amylovora.

Authors:  Luisa F Castiblanco; Lindsay R Triplett; George W Sundin
Journal:  Front Microbiol       Date:  2018-02-08       Impact factor: 5.640
  5 in total

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