Literature DB >> 2548444

In vitro activity of SK&F 104662, a new glycopeptide antibiotic.

J D Yao1, G M Eliopoulos, R C Moellering.   

Abstract

The in vitro activity of SK&F 104662, a new glycopeptide antibiotic, against gram-positive bacteria was evaluated. Activity was comparable to those of teicoplanin and vancomycin against most organisms. SK&F 104662 inhibited diphtheroids at concentrations of less than or equal to 0.5 microgram/ml. Addition of human serum to the test medium lowered the inhibitory activity of this glycopeptide against some organisms by as much as eightfold.

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Year:  1989        PMID： 2548444      PMCID： PMC284265          DOI： 10.1128/AAC.33.6.965

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  5 in total

1.  Comparative synergistic activity of nafcillin, oxacillin, and methicillin in combination with gentamicin against.

Authors:  R H Glew; R S Millering; C Wennersten
Journal:  Antimicrob Agents Chemother       Date:  1975-06       Impact factor: 5.191

2.  In vitro activity and mechanism of action of A21978C1, a novel cyclic lipopeptide antibiotic.

Authors:  G M Eliopoulos; C Thauvin; B Gerson; R C Moellering
Journal:  Antimicrob Agents Chemother       Date:  1985-03       Impact factor: 5.191

3.  Diphtheroid prosthetic valve endocarditis. A study of clinical features and infecting organisms.

Authors:  B E Murray; A W Karchmer; R C Moellering
Journal:  Am J Med       Date:  1980-12       Impact factor: 4.965

4.  Method of reliable determination of minimal lethal antibiotic concentrations.

Authors:  R D Pearson; R T Steigbigel; H T Davis; S W Chapman
Journal:  Antimicrob Agents Chemother       Date:  1980-11       Impact factor: 5.191

5.  Transferable beta-lactamase. A new mechanism for in vitro penicillin resistance in Streptococcus faecalis.

Authors:  B E Murray; B Mederski-Samaroj
Journal:  J Clin Invest       Date:  1983-09       Impact factor: 14.808
  5 in total
  3 in total

Review 1.  Therapy of enterococcal infections.

Authors:  G M Eliopoulos; C T Eliopoulos
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1990-02       Impact factor: 3.267

2.  Efficacy of teicoplanin in two dosage regimens for experimental endocarditis caused by a beta-lactamase-producing strain of Enterococcus faecalis with high-level resistance to gentamicin.

Authors:  J D Yao; C Thauvin-Eliopoulos; G M Eliopoulos; R C Moellering
Journal:  Antimicrob Agents Chemother       Date:  1990-05       Impact factor: 5.191

3.  Comparative in vitro activity of the new glycopeptide SK&F 104662 against problematic gram-positive bacteria.

Authors:  F Soriano; J Zapardiel; R Fernández-Roblas
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-09       Impact factor: 3.267
  3 in total

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