| Literature DB >> 25481372 |
Jin-Bo Zhang1, Ming-Li Liu1, Chang Li2, Yan Zhang3, Yi Dai4, Xin-Sheng Yao5.
Abstract
Four new nardosinane-type sesquiterpenoids nardosinanones F-I (1-2, 4-5), along with eight known sesquiterpenoids (3, 6-12) were isolated from the underground parts of Nardostachys chinensis Batal. Their structures were elucidated on the basis of extensive spectroscopic analysis. Compounds 1 and 2 were new nardosinane sesquiterpenoids processing a rare 4,11-epoxy group in nature. In addition, compounds 1, 5-7, 11 and 12 showed protective effects on neonatal rat cardiomyocyte injury induced by hydrogen peroxide.Entities:
Keywords: Myocardial injury; Nardosinane-type sesquiterpenoids; Nardostachys chinensis Batal
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Year: 2014 PMID: 25481372 DOI: 10.1016/j.fitote.2014.11.020
Source DB: PubMed Journal: Fitoterapia ISSN: 0367-326X Impact factor: 2.882