Elif Akdogan1, Kemal Turkyilmaz2, Teslime Ayaz3, Damla Tufekci3. 1. Department of Haematology, School of Medicine, Recep Tayyip Erdogan University, Rize, Turkey altunelif@hotmail.com. 2. Department of Ophthalmology, School of Medicine, Recep Tayyip Erdogan University, Rize, Turkey. 3. Department of Internal Medicine, School of Medicine, Recep Tayyip Erdogan University, Rize, Turkey.
Abstract
OBJECTIVE: To evaluate peripapillary retinal nerve fibre layer (RNFL) thickness in adult women with iron deficiency anaemia and healthy control subjects. METHODS: Women with iron deficiency anaemia and age- and sex-matched healthy control subjects were sequentially recruited and underwent detailed ophthalmic examination, including spectral-domain optical coherence tomography (OCT). Serum haemoglobin (Hb), iron and ferritin concentrations, total iron-binding capacity (TIBC) and mean corpuscular volume were determined. RESULTS: Peripapillary RNFL thicknesses in the nasal and inferior quadrants were significantly smaller in patients (n = 40) than in controls (n = 40). In the patient group, there were significant correlations between inferior quadrant RNFL thickness and Hb, and between nasal quadrant RNFL thickness and serum iron and ferritin concentrations, and TIBC. CONCLUSION: Iron deficiency anaemia reduces RNFL thickness in adult women.
OBJECTIVE: To evaluate peripapillary retinal nerve fibre layer (RNFL) thickness in adult women with iron deficiency anaemia and healthy control subjects. METHODS:Women with iron deficiency anaemia and age- and sex-matched healthy control subjects were sequentially recruited and underwent detailed ophthalmic examination, including spectral-domain optical coherence tomography (OCT). Serum haemoglobin (Hb), iron and ferritin concentrations, total iron-binding capacity (TIBC) and mean corpuscular volume were determined. RESULTS: Peripapillary RNFL thicknesses in the nasal and inferior quadrants were significantly smaller in patients (n = 40) than in controls (n = 40). In the patient group, there were significant correlations between inferior quadrant RNFL thickness and Hb, and between nasal quadrant RNFL thickness and serum iron and ferritin concentrations, and TIBC. CONCLUSION:Iron deficiency anaemia reduces RNFL thickness in adult women.
Authors: Hasan Basri Arifoglu; Bekir Kucuk; Necati Duru; Orhan Altunel; Ahmet Gulhan; Mustafa Ozen; Bilal Aygun; Mustafa Atas Journal: Int Ophthalmol Date: 2017-01-04 Impact factor: 2.031