Dipayan Sen1, Sambuddha Ghosh2, Debesh Roy1. 1. Regional Institute of Ophthalmology and Department of Biochemistry, Medical College, 88 College Street, Kolkata 700073, India. 2. Regional Institute of Ophthalmology and Department of Biochemistry, Medical College, 88 College Street, Kolkata 700073, India. Electronic address: sambuddhaghosh@gmail.com.
Abstract
BACKGROUND: Association of C-reactive protein (CRP) and body mass index (BMI) with diabetic retinopathy (DR) has conflicting reports. METHOD: Sixty diabetes patients each with DR (Group A), no DR (Group B) and 60 healthy volunteers (control, group C) were studied. CRP was measured. BMI was calculated. RESULT: Significant difference in CRP was observed between groups A & B (p=0.000) and A & C (p=0.007). No significant difference in BMI was observed. Central macular thickness correlated positively with CRP and negatively with BMI. CONCLUSION: We observed strong association of CRP with DR and no significant relationship between DR and BMI.
BACKGROUND: Association of C-reactive protein (CRP) and body mass index (BMI) with diabetic retinopathy (DR) has conflicting reports. METHOD: Sixty diabetespatients each with DR (Group A), no DR (Group B) and 60 healthy volunteers (control, group C) were studied. CRP was measured. BMI was calculated. RESULT: Significant difference in CRP was observed between groups A & B (p=0.000) and A & C (p=0.007). No significant difference in BMI was observed. Central macular thickness correlated positively with CRP and negatively with BMI. CONCLUSION: We observed strong association of CRP with DR and no significant relationship between DR and BMI.
Authors: Mayara Karla Dos Santos Nunes; Alexandre Sérgio Silva; Isabella Wanderley de Queiroga Evangelista; João Modesto Filho; Cecília Neta Alves Pegado Gomes; Rayner Anderson Ferreira do Nascimento; Rafaella Cristhine Pordeus Luna; Maria José de Carvalho Costa; Naila Francis Paulo de Oliveira; Darlene Camati Persuhn Journal: Diabetol Metab Syndr Date: 2017-10-18 Impact factor: 3.320