Successful transcatheter aortic valve implantation for pure aortic regurgitation using a new second generation self-expanding J-Valve(TM) system - the first in-man implantation.

Transcatheter aortic valve implantation (TAVI) has been recognised as an effective treatment option for high-risk or inoperable patients with aortic stenosis. However, experience with TAVI for non-calcified aortic regurgitation is still limited. The new J-Valve(TM) prosthesis is designed for antegrade transapical implantation which is characterised by three U-shape graspers that could facilitate intuitive 'self-positioning' valve implantation and provide axial as well as radial fixation by embracing the native valve leaflets. Here we report the first in-man TAVI procedure of J-Valve(TM) prosthesis in a high risk patient with pure aortic regurgitation.