| Literature DB >> 25457492 |
Meng Wang1, Li-Xin Gao2, Jue Wang1, Jing-Ya Li2, Mei-Hua Yu1, Jia Li2, Ai-Jun Hou3.
Abstract
Eight Diels-Alder adducts, morbilisins A-H (1-8), a known analogue, chalcomoracin (9), together with eleven known flavonoids and 2-arylbenzofurans, were isolated from the leaves of Morus notabilis. Their structures were elucidated by extensive spectroscopic analysis, including 1D, 2D NMR, MS, and ECD data. Compounds 1, 5, and 7-9 showed inhibition against PTP1B phosphatase activity in vitro.Entities:
Keywords: Diels–Alder adducts; Moraceae; Morbilisins A–H; Morus notabilis; Protein tyrosine phosphatase 1B
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Year: 2014 PMID： 25457492 DOI： 10.1016/j.phytochem.2014.10.015
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072