Literature DB >> 2545039

Eclipse products of poliovirus after cold-synchronized infection of HeLa cells.

L Everaert1, R Vrijsen, A Boeyé.   

Abstract

The particles derived from radioactively labeled poliovirus, in cold-synchronized infection of HeLa cells, were studied. After temperatures shift-up, radioactivity was transferred rapidly from the infecting virions (160 S) to 135 S, and from there more slowly to 110 S, a previously unreported eclipse product. Both the 135 and 110 S particles contained RNA, lacked VP4, and were H-antigenic. In the 135 S particles, part of the VP1 complement was lost; in addition to this, the VP2 polypeptide of the 110 S particles was cleaved in situ. The formation of eclipse products was insensitive to cycloheximide. Arildone totally blocked the formation of 135 S particles, but not their further processing.

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Year:  1989        PMID： 2545039     DOI： 10.1016/0042-6822(89)90512-6

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  26 in total

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Authors:  V L Giranda; B A Heinz; M A Oliveira; I Minor; K H Kim; P R Kolatkar; M G Rossmann; R R Rueckert
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2.  Picornaviruses.

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3.  Kinetics of poliovirus uncoating in HeLa cells in a nonacidic environment.

Authors:  M Gromeier; K Wetz
Journal:  J Virol       Date:  1990-08       Impact factor: 5.103

4.  Cell-induced conformational change in poliovirus: externalization of the amino terminus of VP1 is responsible for liposome binding.

Authors:  C E Fricks; J M Hogle
Journal:  J Virol       Date:  1990-05       Impact factor: 5.103

5.  Mechanism of action and capsid-stabilizing properties of VHHs with an in vitro antipolioviral activity.

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6.  Uncoating of human rhinovirus serotype 2 from late endosomes.

Authors:  E Prchla; E Kuechler; D Blaas; R Fuchs
Journal:  J Virol       Date:  1994-06       Impact factor: 5.103

7.  Effect of a capsid-stabilizing pyridazinamine, R 78206, on the eclipse and intracellular location of poliovirus.

Authors:  O Ofori-Anyinam; R Vrijsen; P Kronenberger; A Boeyé
Journal:  J Virol       Date:  1993-04       Impact factor: 5.103

8.  Interactions of foot-and-mouth disease virus with soluble bovine alphaVbeta3 and alphaVbeta6 integrins.

Authors:  Hernando Duque; Michael LaRocco; William T Golde; Barry Baxt
Journal:  J Virol       Date:  2004-09       Impact factor: 5.103

9.  Chloroquine induces empty capsid formation during poliovirus eclipse.

Authors:  P Kronenberger; R Vrijsen; A Boeyé
Journal:  J Virol       Date:  1991-12       Impact factor: 5.103

10.  Mouse adaptation determinants of poliovirus type 1 enhance viral uncoating.

Authors:  T Couderc; F Delpeyroux; H Le Blay; B Blondel
Journal:  J Virol       Date:  1996-01       Impact factor: 5.103
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