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Literature DB >> 25447164

Five new eudesmane-type sesquiterpenoids from Chinese agarwood induced by artificial holing.

Wei Li¹, Cai-Hong Cai¹, Zhi-Kai Guo¹, Hao Wang¹, Wen-Jian Zuo¹, Wen-Hua Dong¹, Wen-Li Mei², Hao-Fu Dai³.

Abstract

Five new eudesmane-type sesquiterpenoids (1-5), along with six known ones (6-11), were isolated from Chinese agarwood induced by artificial holing originating from Aquilaria sinensis (Lour.) Gilg (Thymelaeaceae). The structures of the new sesquiterpenoids were established by spectroscopic methods including UV, IR, MS, 1D, and 2D NMR. Compounds 1, 3, 6 and 7 exhibited antibacterial activities against both Staphylococcus aureus and Ralstonia solanacearum, and compound 5 only showed an inhibitory activity towards S. aureus. Compounds 1, 6, 7 and 10 showed weak acetylcholinesterase inhibitory activity.

Entities: Chemical Species

Keywords: AChE inhibitory activities; Agarwood induced by artificial holing; Antibacterial activities; Aquilaria sinensis (Lour.) Gilg; Sesquiterpenoids; Thymelaeaceae

Mesh：

Substances：

Year: 2014 PMID： 25447164 DOI： 10.1016/j.fitote.2014.11.010

Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882

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Cited

15 in total

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Authors: Phattarawadee Nun-Anan; Sunisa Suchat; Narissara Mahathaninwong; Narong Chueangchayaphan; Seppo Karrila; Suphatchakorn Limhengha
Journal: Polymers (Basel) Date: 2021-11-29 Impact factor: 4.329

Review 2. Acetylcholinesterase Inhibitory Potential of Various Sesquiterpene Analogues for Alzheimer's Disease Therapy.

Authors: Ashwani Arya; Rubal Chahal; Rekha Rao; Md Habibur Rahman; Deepak Kaushik; Muhammad Furqan Akhtar; Ammara Saleem; Shaden M A Khalifa; Hesham R El-Seedi; Mohamed Kamel; Ghadeer M Albadrani; Mohamed M Abdel-Daim; Vineet Mittal
Journal: Biomolecules Date: 2021-02-25

3. UPLC-MS-guided isolation of single ether linkage dimeric 2-(2-phenylethyl)chromones from Aquilaria sinensis.

Authors: Tongdong Kuang; Hui-Qin Chen; Hao Wang; Fan-Dong Kong; Cai-Hong Cai; Wen-Hua Dong; Jing-Zhe Yuan; Wen-Li Mei; Hao-Fu Dai
Journal: RSC Adv Date: 2019-05-31 Impact factor: 4.036

Review 4. Review: Secondary Metabolites of Aquilaria, a Thymelaeaceae Genus.

Authors: Alfinda Novi Kristanti; Mulyadi Tanjung; Nanik Siti Aminah
Journal: Mini Rev Org Chem Date: 2018-02 Impact factor: 2.495

5. GYF-21, an Epoxide 2-(2-Phenethyl)-Chromone Derivative, Suppresses Innate and Adaptive Immunity via Inhibiting STAT1/3 and NF-κB Signaling Pathways.

Authors: Ran Guo; Yun-Fang Zhao; Jun Li; Yu-Fan Gu; Hui-Xia Huo; Shan-Shan Li; Yue-Lin Song; Zhi-Xiang Zhu; Peng-Fei Tu
Journal: Front Pharmacol Date: 2017-05-22 Impact factor: 5.810

6. 2-(2-Phenylethyl)chromone Derivatives of Agarwood Originating from Gyrinops salicifolia.

Authors: Hang Shao; Wen-Li Mei; Wen-Hua Dong; Cui-Juan Gai; Wei Li; Guo-Peng Zhu; Hao-Fu Dai
Journal: Molecules Date: 2016-10-03 Impact factor: 4.411

7. GC-MS Study of the Chemical Components of Different Aquilaria sinensis (Lour.) Gilgorgans and Agarwood from Different Asian Countries.

Authors: Meng-Ru Wang; Wei Li; Sha Luo; Xin Zhao; Chun-Hui Ma; Shou-Xin Liu
Journal: Molecules Date: 2018-08-28 Impact factor: 4.411