| Literature DB >> 25444675 |
Masayoshi Tojo1, Momoko Mawatari2, Kayoko Hayakawa2, Maki Nagamatsu3, Kayo Shimada4, Kazuhisa Mezaki5, Yuko Sugiki6, Emi Kuroda6, Nozomi Takeshita2, Satoshi Kutsuna2, Yoshihiro Fujiya2, Tohru Miyoshi-Akiyama4, Teruo Kirikae7, Norio Ohmagari2.
Abstract
We report a case of multidrug-resistant (MDR) Acinetobactor baumannii isolates obtained from a traveler returned from Brunei. Whole-genome sequencing analysis revealed that the isolates harbored blaOxA-23 and armA. The minimum inhibitory concentrations of antibiotics against the strain were as follows: imipenem, 32 μg/ml; meropenem, 32 μg/ml; ciprofloxacin, 16 μg/ml; amikacin, ≧ 1024 μg/ml; arbekacin, ≧ 1024 μg/ml; aztreonam, 64 μg/ml; colistin, 4 μg/ml. A. baumannii harboring both blaOxA-23 and armA is rarely reported in Japan, and, to the best of our knowledge, this is the second report of A. baumannii harboring both resistant genes in Japan.Entities:
Keywords: 16S rRNA methylase; Acinetobacter baumannii; Antimicrobial resistance; Carbapenemase; armA; bla(OxA-23)
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Year: 2014 PMID： 25444675 DOI： 10.1016/j.jiac.2014.08.029
Source DB: PubMed Journal: J Infect Chemother ISSN： 1341-321X Impact factor: 2.211