| Literature DB >> 25442305 |
Yan-Ni Shi1, Zheng-Chao Tu2, Xin-Long Wang3, Yong-Ming Yan1, Ping Fang3, Zhi-Li Zuo3, Bo Hou3, Tong-Hua Yang4, Yong-Xian Cheng5.
Abstract
Recent studies focusing on unveiling the biological agents of Aspongopus chinensis have led to the identification of four new norepinephrine derivatives (1-4), three new sesquiterpenoids (5-7), and one new lactam (8). In addition, twenty-three known compounds have been identified, most of which were isolated from this insect for the first time. Selected members of insect-derived substances were evaluated for their biological activities against renal protection in high-glucose-induced mesangial cells and COX-2 inhibition.Entities:
Keywords: Aspongopus chinensis; Biological evaluation; Insects; Lactam; Norepinephrine derivatives; Sesquiterpenoids
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Year: 2014 PMID： 25442305 DOI： 10.1016/j.bmcl.2014.09.083
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823