Literature DB >> 25440884

Synthetic derivatives of aromatic abietane diterpenoids and their biological activities.

Miguel A González1.   

Abstract

Naturally occurring aromatic abietane diterpenoids (dehydroabietanes) exhibit a wide range of biological activities. A number of synthetic studies aimed at modifying the abietane skeleton in order to obtain new potential chemotherapeutic agents have been reported. In this study, the biological activities of synthetic derivatives of aromatic abietane diterpenoids are reviewed.
Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Abietane; Carnosic acid; Dehydroabietic acid; Dehydroabietylamine; Diterpenoid; Ferruginol

Mesh：

Substances：

Year:  2014        PMID： 25440884     DOI： 10.1016/j.ejmech.2014.10.023

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  9 in total

1.  Facile synthesis of 1,2-dione-containing abietane analogues for the generation of human carboxylesterase inhibitors.

Authors:  Randall J Binder; M Jason Hatfield; Liying Chi; Philip M Potter
Journal:  Eur J Med Chem       Date:  2018-02-19       Impact factor: 6.514

2.  Royleanone Derivatives From Plectranthus spp. as a Novel Class of P-Glycoprotein Inhibitors.

Authors:  Catarina Garcia; Vera M S Isca; Filipe Pereira; Carlos M Monteiro; Epole Ntungwe; Francisco Sousa; Jelena Dinic; Suvi Holmstedt; Amílcar Roberto; Ana Díaz-Lanza; Catarina P Reis; Milica Pesic; Nuno R Candeias; Ricardo J Ferreira; Noélia Duarte; Carlos A M Afonso; Patrícia Rijo
Journal:  Front Pharmacol       Date:  2020-11-17       Impact factor: 5.810

3.  Synthesis of bodinieric acids A and B, both C-18 and C-19-functionalized abietane diterpenoids: DFT study of the key aldol reaction.

Authors:  Ramón J Zaragozá; Miguel A González-Cardenete
Journal:  RSC Adv       Date:  2020-04-16       Impact factor: 4.036

4.  Synthesis and evaluation of diterpenic Mannich bases as antiviral agents against influenza A and SARS-CoV-2.

Authors:  Elena V Tret'yakova; Xinyuan Ma; Oxana B Kazakova; Anna A Shtro; Galina D Petukhova; Artem M Klabukov; Danil S Dyatlov; Anna A Smirnova; Huan Xu; Sulong Xiao
Journal:  Phytochem Lett       Date:  2022-08-02       Impact factor: 1.873

Review 5.  Antiviral Profiling of C-18- or C-19-Functionalized Semisynthetic Abietane Diterpenoids.

Authors:  Miguel A González-Cardenete; Damir Hamulić; Francisco J Miquel-Leal; Natalia González-Zapata; Orlando J Jimenez-Jarava; Yaneth M Brand; Laura C Restrepo-Mendez; Marlen Martinez-Gutierrez; Liliana A Betancur-Galvis; Maria L Marín
Journal:  J Nat Prod       Date:  2022-08-15       Impact factor: 4.803

Review 6.  A recent update on new synthetic chiral compounds with antileishmanial activity.

Authors:  Michele Verboni; Diego Olivieri; Simone Lucarini
Journal:  Chirality       Date:  2022-08-10       Impact factor: 2.183

7.  Dehydroabietic oximes halt pancreatic cancer cell growth in the G1 phase through induction of p27 and downregulation of cyclin D1.

Authors:  Laura E Kolsi; Ana S Leal; Jari Yli-Kauhaluoma; Karen T Liby; Vânia M Moreira
Journal:  Sci Rep       Date:  2018-10-29       Impact factor: 4.379

8.  Anti-herpetic and anti-dengue activity of abietane ferruginol analogues synthesized from (+)-dehydroabietylamine.

Authors:  Vicky C Roa-Linares; Yaneth M Brand; Lee S Agudelo-Gomez; Verónica Tangarife-Castaño; Liliana A Betancur-Galvis; Juan C Gallego-Gomez; Miguel A González
Journal:  Eur J Med Chem       Date:  2015-11-11       Impact factor: 6.514

9.  Synthesis and Antiproliferative Evaluation of Novel Hybrids of Dehydroabietic Acid Bearing 1,2,3-Triazole Moiety.

Authors:  Fang-Yao Li; Lin Huang; Qian Li; Xiu Wang; Xian-Li Ma; Cai-Na Jiang; Xiao-Qun Zhou; Wen-Gui Duan; Fu-Hou Lei
Journal:  Molecules       Date:  2019-11-19       Impact factor: 4.411
  9 in total

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